Clinical trial for Acute Ischemic Stroke
Official title Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions
ClinicalTrials.gov ID: NCT06029491
What this study is testing
- What it's testing
- The study will look at how safe and effective the RapidPulse aspiration system is for removing clots in acute ischemic stroke patients.
- Who it's for
- Adults who have had a stroke and can be treated within 8 hours of symptom onset.
- What's involved
- Participants will receive a mechanical thrombectomy using the RapidPulse device and will have follow‑up visits and tests to monitor safety and outcomes.
- Time commitment
- The study lasts 90 days, with several clinic visits and tests during that period.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- Age 18 to 85 years
- Clinical diagnosis of acute ischemic stroke with NIH Stroke Scale (NIHSS) score ≥ 6
- Able to be treated within 8 hours of symptom onset or last known normal (LKN)
- Able to be treated within 120 minutes from the time of the qualifying baseline CT/MR image
- Pre-morbid Modified Rankin Scale (mRS) score 0-1
You likely can't join if
- Intracranial Hemorrhage (ICH)
- Significant mass effect and/or midline shift
- Alberta Stroke Program Early CT Score (ASPECTS) \<6 or (PC-ASPECTS \<8 on CT angiography source images or DWI MRI for posterior circulation stroke)
- Intracranial Atherosclerotic Disease (ICAD)
- Multiple or tandem occlusions
- Life expectancy less than 6 months
See the full eligibility criteria
- Age 18 to 85 years
- Clinical diagnosis of acute ischemic stroke with NIH Stroke Scale (NIHSS) score ≥ 6
- Able to be treated within 8 hours of symptom onset or last known normal (LKN)
- Able to be treated within 120 minutes from the time of the qualifying baseline CT/MR image
- Pre-morbid Modified Rankin Scale (mRS) score 0-1
- Angiographic confirmation of large vessel occlusion (LVO) in the anterior (intracranial ICA or MCA M1 or M2 segments) or posterior circulation (vertebral or basilar arteries) as confirmed by digital subtraction...
- Candidate to receive treatment with ADAPT technique (Direct Aspiration First-Pass Technique)
- Intracranial Hemorrhage (ICH)
- Significant mass effect and/or midline shift
- Alberta Stroke Program Early CT Score (ASPECTS) \<6 or (PC-ASPECTS \<8 on CT angiography source images or DWI MRI for posterior circulation stroke)
- Intracranial Atherosclerotic Disease (ICAD)
- Multiple or tandem occlusions
- Life expectancy less than 6 months
The study team makes the final eligibility decision.
Where it is enrolling
- Torrance, California, United States
- New Haven, Connecticut, United States
- Jacksonville, Florida, United States
- Tampa, Florida, United States
- Atlanta, Georgia, United States
- Chicago, Illinois, United States
- Park Ridge, Illinois, United States
- Iowa City, Iowa, United States
- St Louis, Missouri, United States
- Buffalo, New York, United States
- New York, New York, United States
- Memphis, Tennessee, United States
- Harlingen, Texas, United States
- Alicante, Spain
- Badalona, Spain
- Barcelona, Spain
- Madrid, Spain
- Istanbul, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Torrance, California, United States; New Haven, Connecticut, United States; Jacksonville, Florida, United States; Tampa, Florida, United States; Atlanta, Georgia, United States; Chicago, Illinois, United States and 12 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.