Clinical trial for Kidney Disease, End-Stage
Official title Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates
ClinicalTrials.gov ID: NCT06089473
What this study is testing
- What it's testing
- The study wants to see if a 12‑week virtual pre‑hab program (plus up to 5 months of home exercise) is doable and acceptable for kidney transplant candidates, and to gather data for planning a larger trial.
- Who it's for
- Adults who are on the waiting list for a kidney transplant and have end‑stage kidney disease and signs of frailty.
- What's involved
- Participants are randomly assigned to either a virtual program that includes guided exercise and education you do at home, or to usual outpatient care. The program lasts 12 weeks, followed by up to 5 months of independent home exercises, with virtual check‑ins and questionnaires.
- Time commitment
- Up to 8 months total, with regular virtual visits and home exercise sessions throughout the 12‑week program and the maintenance phase.
- Time commitment: about 9 months
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- consecutive individuals with end stage kidney disease (ESKD) (aged ≥18 years), classified as pre-frail (1-2 points), frail (3-4 points) or very frail...
- English or French speakers
- is technologically capable of connecting (either independently or through household members/next-of-kin) with an online videoconferencing platform...
You likely can't join if
- are classified as robust (0 points) on their Fried's frailty phenotype score
- are participating in a structured exercise program (hospital-based or home-based or another trial)
- are waiting for kidney-pancreas or kidney-liver transplant as those have much longer waiting time
- are hospitalized for any reason during the assessment for eligibility
- have a cPRA (calculated panel reactive antibodies) \>95% and are on the highly sensitized exchange program and expected to have a prolonged waiting...
- are expected to have a transplant before the end of the 12 week-intervention (e.g.
See the full eligibility criteria
- consecutive individuals with end stage kidney disease (ESKD) (aged ≥18 years), classified as pre-frail (1-2 points), frail (3-4 points) or very frail (5 points) on the Fried's frailty phenotype and who are accepted or...
- English or French speakers
- is technologically capable of connecting (either independently or through household members/next-of-kin) with an online videoconferencing platform through an e-mail invitation (Patients who do not have access to...
- are classified as robust (0 points) on their Fried's frailty phenotype score
- are participating in a structured exercise program (hospital-based or home-based or another trial)
- are waiting for kidney-pancreas or kidney-liver transplant as those have much longer waiting time
- are hospitalized for any reason during the assessment for eligibility
- have a cPRA (calculated panel reactive antibodies) \>95% and are on the highly sensitized exchange program and expected to have a prolonged waiting times on the waiting list
- are expected to have a transplant before the end of the 12 week-intervention (e.g. individuals who will receive an organ from a living donor or are type A blood
- have pre-existing or newly identified significant cognitive impairment
- have pre-existing or newly identified cardiac, musculoskeletal, neuropathy or neurological condition that might affect their exercise performance or otherwise render rehabilitation participation unsafe
The study team makes the final eligibility decision.
Where it is enrolling
- Montreal, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 9 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Montreal, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.