Insomnia study: Lemborexant
Official title Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial
ClinicalTrials.gov ID: NCT06093126
What this study is testing
What is Lemborexant?
An investigational oral medication being studied as a potential treatment for insomnia. It is designed to block orexin receptors (OX1R and OX2R) that promote wakefulness.
Also referred to as Belsomra.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to see how well Lemborexant helps sleep and how well it is tolerated in someone with early‑onset dementia.
- Who it's for
- Adults who have early‑onset dementia and trouble sleeping.
- What's involved
- Participants will take Lemborexant and keep a sleep diary, with regular check‑in visits to record sleep quality and side effects.
- Time commitment
- The trial lasts several weeks and requires a few scheduled visits to monitor progress.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults
You may be able to join if
- Identified by clinician investigator to have early-onset dementia and a significant component of insomnia.
You likely can't join if
- Known sleep disorders that are contraindications for orexin antagonist therapy.
The study team makes the final eligibility decision.
Where it is enrolling
- Halifax, Nova Scotia, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Halifax, Nova Scotia, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.