Liver Dysfunction study: High-Dose Insulin Therapy
Official title Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration
ClinicalTrials.gov ID: NCT06126419
What this study is testing
What is High-Dose Insulin Therapy?
This is an investigational treatment being studied to see if it can improve liver function before major liver surgery. It is designed to keep insulin levels high while maintaining normal blood sugar levels to potentially support liver health.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether high-dose insulin improves liver function before surgery. It also looks at how this treatment affects liver growth after a specific procedure.
- Who it's for
- You may be able to join if you are scheduled for major liver surgery.
- What's involved
- You would get an insulin and sugar drip for six hours. This happens in the weeks before your planned surgery.
- Time commitment
- The study lasts for the weeks leading up to your surgery.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age \> 18 years old
- Candidate for major liver resection
- Resectable colorectal liver metastasis
You likely can't join if
- Inability to give consent
- Type 1 diabetes mellitus
- Uncontrolled blood glucose levels (fasting level \> 10 mmol/L)
- Unresectable colorectal liver metastasis
- Extrahepatic metastatic disease that is unresectable
The study team makes the final eligibility decision.
Where it is enrolling
- Montreal, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Montreal, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.