Long COVID study: WATER+CT
Official title Water-based Activity to Enhance Recovery in Long COVID-19
ClinicalTrials.gov ID: NCT06142253
What this study is testing
- What it's testing
- The study wants to see if a combined aquatic exercise and cognitive training program is safe and doable, and whether it might help neurological problems from long COVID.
- Who it's for
- Adults who have long‑COVID with neurological symptoms such as memory or thinking difficulties.
- What's involved
- Participants will first do a guided water‑exercise program, then move on to memory and thinking training sessions, with regular check‑ins and simple tests to track progress.
- Time commitment
- The study runs for up to two years, with participants attending scheduled exercise and training sessions and follow‑up visits throughout the period.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 89
You may be able to join if
- Veterans, age 18 to 89, of any racial or ethnic group
- Previous COVID-19 infection at least 6 months after diagnosis documented in clinical record
- Persistent neurological symptoms (e.g., "brain fog", cognitive impairment) occurring within 3 months of onset of COVID-19 infection and lasting at...
- Visual and auditory acuity to allow neuropsychological testing
- Willingness to participate in clinical trial for 8 months
You likely can't join if
- Psychiatric Exclusions
- Current, uncontrolled severe psychotic disorder determined by the Mini International Neuropsychiatric Interview (MINI) Medical Exclusions
- History of neurological (e.g., multiple sclerosis, seizure disorder, stroke,) neurodegenerative (e.g., Parkinson's disease, Alzheimer's disease) or...
- Current severe cardiac disease (e.g., uncontrolled atrial fibrillation, defined as mean 24 hour heart rate \>85 beats/min, or 24 hour maximal...
- Inability to participate in an exercise stress test
- Inability to read, verbalize understanding and voluntarily sign the Informed Consent
See the full eligibility criteria
- Veterans, age 18 to 89, of any racial or ethnic group
- Previous COVID-19 infection at least 6 months after diagnosis documented in clinical record
- Persistent neurological symptoms (e.g., "brain fog", cognitive impairment) occurring within 3 months of onset of COVID-19 infection and lasting at least 8 weeks in duration
- Visual and auditory acuity to allow neuropsychological testing
- Willingness to participate in clinical trial for 8 months
- Approval by Primary Care Provider to participate in water-based physical exercise
- Psychiatric Exclusions
- Current, uncontrolled severe psychotic disorder determined by the Mini International Neuropsychiatric Interview (MINI) Medical Exclusions
- History of neurological (e.g., multiple sclerosis, seizure disorder, stroke,) neurodegenerative (e.g., Parkinson's disease, Alzheimer's disease) or system illness affecting CNS function (e.g., liver failure, kidney...
- Current severe cardiac disease (e.g., uncontrolled atrial fibrillation, defined as mean 24 hour heart rate \>85 beats/min, or 24 hour maximal ventricular rate \>150 beats/min
- Inability to participate in an exercise stress test
- Inability to read, verbalize understanding and voluntarily sign the Informed Consent
The study team makes the final eligibility decision.
Where it is enrolling
- Palo Alto, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 89 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Palo Alto, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.