Long-COVID study: COVIDEx
Official title Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
ClinicalTrials.gov ID: NCT06156176
What this study is testing
- What it's testing
- This study checks if a new rehab program called COVIDEx works better than standard care for treating fatigue after COVID-19.
- Who it's for
- People who have had COVID-19 and are still experiencing fatigue.
- What's involved
- Participants will be randomly assigned to either the new 8-week exercise program or standard care. The new program includes two 50-minute sessions per week.
- Time commitment
- The study lasts 24 weeks, including the 8-week treatment period and follow-up visits.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adults of at least 18 years of age
- Able to provide informed consent
- Can speak and understand English
- Documented history of SARS-CoV-2 infection (positive PCR/antigen test during acute illness or clinical diagnosis by physician during or after the...
- Fatigue symptoms within 3 months of COVID-19 infection, lasting at least 2 months
You likely can't join if
- Active SARS-CoV-2 infection
- Pre-existing physical, cognitive, and/or mental health conditions that make exercise contraindicated, consent unattainable, or that cause symptoms...
- Inability to follow study procedures
- Pregnant and/or breastfeeding
- Received investigational agents as part of a separate study within 30 days of the screening visit
- Has any type of metal bodily implant in head or heart (i.e., pins, plates, pacemakers)
See the full eligibility criteria
- Adults of at least 18 years of age
- Able to provide informed consent
- Can speak and understand English
- Documented history of SARS-CoV-2 infection (positive PCR/antigen test during acute illness or clinical diagnosis by physician during or after the acute illness)
- Fatigue symptoms within 3 months of COVID-19 infection, lasting at least 2 months
- Fatigue symptoms cannot be explained by an alternative diagnosis
- Fatigue symptoms may be new onset following initial recovery from an acute COVID-19 infection or persist from the initial illness
- Fatigue symptoms may have an episodic nature, fluctuate or relapse over time
- Minimal functional capability: able to walk 10-15 minutes and be recovered within 30-60 minutes or without significant post-exertional malaise (PEM)
- Has applicable technology to access Microsoft Teams and Webex (i.e., computer, laptop, tablet)
- Active SARS-CoV-2 infection
- Pre-existing physical, cognitive, and/or mental health conditions that make exercise contraindicated, consent unattainable, or that cause symptoms similar to those seen in post COVID-19 (e.g., major neurocognitive...
- Inability to follow study procedures
- Pregnant and/or breastfeeding
- Received investigational agents as part of a separate study within 30 days of the screening visit
- Has any type of metal bodily implant in head or heart (i.e., pins, plates, pacemakers)
- Current participation in other studies related to COVID-19, exercise, and/or fatigue interventions OR participation within 30 days of the screening visit
The study team makes the final eligibility decision.
Where it is enrolling
- London, Ontario, Canada
Compensation & support
Some study-related costs may be covered.
No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at London, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.