Clinical trial for Glioblastoma
Official title PH Sensitive MRI Based Resections of Glioblastoma
ClinicalTrials.gov ID: NCT06176066
What this study is testing
- What it's testing
- This study checks if using a new MRI technique to guide surgery is safe. It also looks at whether removing more tumor helps patients live longer without the cancer growing.
- Who it's for
- Adults with newly diagnosed or returning glioblastoma who are healthy enough for surgery and have tumors not in critical brain areas.
- What's involved
- Participants will have a special MRI scan before surgery. During surgery, doctors will use this scan to guide how much tumor to remove. Afterward, they will have regular check-ups and scans.
- Time commitment
- The study involves a hospital stay of 1-3 days for surgery, a follow-up visit in 2 weeks, and an MRI at 4 weeks.
- Phase 1: an early, usually small safety study
This is a blinded study.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Male or female ≥ 18 years of age.
- Written informed consent (and assent when applicable) obtained from subject or subject's legal representative and ability for subject to comply with...
- Karnofsky Performance Scale (KPS) \> 70 (indicating good performance status).
- Individuals with suspected, newly diagnosed or recurrent IDH wild type WHO IV glioblastoma (intraxial, expansile contrast-enhancing mass without...
You likely can't join if
- Male or female \< 18 years of age
- Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data.
- Not medically cleared for surgery as defined by standard pre-operative neurosurgery guidelines for open craniotomy for resection (not-biopsy) of...
- Involvement of eloquent areas (as defined by MRI signal clearly involving areas that would lead to a qualifying neurologic deficit as defined in...
The study team makes the final eligibility decision.
Where it is enrolling
- Los Angeles, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Los Angeles, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.