Hypertension, Pregnancy-Induced study: Nifedipine ER
Official title Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
ClinicalTrials.gov ID: NCT06220721
What this study is testing
What is Nifedipine ER?
an investigational extended‑release oral medicine being studied for intensive postpartum blood pressure control after hypertensive disorders of pregnancy is designed to block calcium channels in blood‑vessel walls, helping the vessels relax and lower blood pressure
Also referred to as Procardia XL, Adalat XL.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether tight blood pressure control after pregnancy hypertension improves heart health and reduces chronic high blood pressure.
- Who it's for
- You may be able to join if you had high blood pressure or preeclampsia during pregnancy.
- What's involved
- You will have your blood pressure checked regularly and may take medicines to keep it low. You will visit the clinic for follow‑up appointments.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, women only
You may be able to join if
- Hypertensive disorders of pregnancy (HDP) diagnosis, specifically gestational hypertension, preeclampsia, eclampsia, or HELLP syndrome, according to...
- Postpartum day 0-4
- Age ≥ 18 years
- Able to communicate in English or in Spanish
- Has an established OBGYN at an MCW or NU health system practice that has access to Epic electronic medical records.
You likely can't join if
- Pre-gestational hypertension
- Type 1 or type 2 diabetes mellitus
- Admitted to intensive care unit at the time of screening
- Diagnosed with HDP during postpartum readmission after discharge from delivery hospitalization
- Getting discharged on the day of screening
- Known allergy or contraindication to nifedipine ER
See the full eligibility criteria
- Hypertensive disorders of pregnancy (HDP) diagnosis, specifically gestational hypertension, preeclampsia, eclampsia, or HELLP syndrome, according to ACOG guidelines
- Postpartum day 0-4
- Age ≥ 18 years
- Able to communicate in English or in Spanish
- Has an established OBGYN at an MCW or NU health system practice that has access to Epic electronic medical records.
- Pre-gestational hypertension
- Type 1 or type 2 diabetes mellitus
- Admitted to intensive care unit at the time of screening
- Diagnosed with HDP during postpartum readmission after discharge from delivery hospitalization
- Getting discharged on the day of screening
- Known allergy or contraindication to nifedipine ER
- Inability or unwillingness to provide informed consent
- Already taking long-acting antihypertensive medication for standard care
- Maternal conditions that impact study outcomes: sickle cell disease, systemic lupus erythematosus
The study team makes the final eligibility decision.
Where it is enrolling
- Chicago, Illinois, United States
- Milwaukee, Wisconsin, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Chicago, Illinois, United States; Milwaukee, Wisconsin, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.