Scleroderma, Systemic study: Diosmin
Official title Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis
ClinicalTrials.gov ID: NCT06256575
What this study is testing
What is Diosmin?
This is an investigational medical food being studied to see if it helps heal open sores on the fingers in people with systemic sclerosis.
Also referred to as Vasculera.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study will look at whether diosmin is safe and can help open finger sores heal in people with systemic sclerosis.
- Who it's for
- People with systemic sclerosis who have open sores on their fingers.
- What's involved
- Participants will visit the clinic four times over eight weeks for physical exams, photos, and questionnaires about pain and lifestyle changes. Two of the three participants will receive the active drug.
- Time commitment
- The study lasts eight weeks with four clinic visits.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Diagnosis of systemic sclerosis (scleroderma)
- At least one "active" digital ulcer
- Medication for systemic sclerosis unchanged for 30 days
You likely can't join if
- Infection or gangrene in ulcer
- Citrus allergy
- Unstable heart, kidney, or liver disease
- Active infection of any type
- Current cancer treatment or uncured cancer
- Pregnancy or breast feeding
The study team makes the final eligibility decision.
Where it is enrolling
- Calgary, Alberta, Canada
- Halifax, Nova Scotia, Canada
- London, Ontario, Canada
- Ottawa, Ontario, Canada
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Calgary, Alberta, Canada; Halifax, Nova Scotia, Canada; London, Ontario, Canada; Ottawa, Ontario, Canada; Toronto, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.