Clinical trial for Acute Lymphoblastic Leukemia
Official title Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma
ClinicalTrials.gov ID: NCT06289673
What this study is testing
What is Dexamethasone?
An investigational corticosteroid being studied as part of a short‑course treatment for newly diagnosed B‑cell acute lymphoblastic leukemia or lymphoblastic lymphoma. It is designed to suppress the immune system and reduce inflammation, which can help kill leukemia cells and control disease spread.
Also referred to as Decadron.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to give enough treatment while doctors determine each patient’s risk of disease coming back, and to collect genetic and clinical data.
- Who it's for
- People who have just been diagnosed with B‑cell acute lymphoblastic leukemia, lymphoblastic lymphoma, or mixed‑type acute leukemia.
- What's involved
- Participants receive standard induction therapy and have tumor samples taken for genetic testing and risk classification. They will have routine clinic visits and lab tests as part of the study.
- Time commitment
- The study follows patients through the initial treatment period, requiring several clinic visits over a few weeks to months.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 1 to 18
You may be able to join if
- Age 1-18.99 years
- Acute lymphoblastic leukemia (ALL) with at least 25% bone marrow blasts or definitive evidence of ALL in peripheral blood (in those without an...
- Lymphoblastic lymphoma (LLy) with immunophenotypic evidence of a lymphoblastic population and \<25% bone marrow blasts and less than 1,000...
- Mixed phenotype acute leukemia (MPAL) with or without 25% bone marrow involvement (i.e. patients with either leukemia or lymphoma are eligible).
You likely can't join if
- Pregnant or breastfeeding
- Receipt of prior cancer directed therapy with the exclusion of up to 1 dose of intrathecal chemotherapy, 1 dose of vincristine, or emergency...
- Known to be currently ineligible for available SJALL therapeutic studies (e.g.
- Inability or unwillingness of research participant or legal guardian/representative to give written informed consent.
- Major pre-existing abnormalities such as ataxia telangiectasia, Fanconi anemia, Charcot Marie Tooth, etc.
The study team makes the final eligibility decision.
Where it is enrolling
- San Diego, California, United States
- Baton Rouge, Louisiana, United States
- Charlotte, North Carolina, United States
- Tulsa, Oklahoma, United States
- Memphis, Tennessee, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 1 year to 18 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at San Diego, California, United States; Baton Rouge, Louisiana, United States; Charlotte, North Carolina, United States; Tulsa, Oklahoma, United States; Memphis, Tennessee, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.