Clinical trial for Atopic Dermatitis
Official title Michigan Food and Atopic Dermatitis (M-FAD) Program - Molecular Analytics Project
ClinicalTrials.gov ID: NCT06300697
What this study is testing
- What it's testing
- The study aims to find out whether atopic dermatitis and food allergy have common genetic or biochemical signals that could help future diagnosis and treatment.
- Who it's for
- People with atopic dermatitis, food allergy, or healthy volunteers are invited to participate.
- What's involved
- Participants will give blood and skin samples at the start, and some may undergo a medically supervised oral food challenge with additional sample collection during the test.
- Time commitment
- The study involves a baseline visit for sample collection and possibly extra visits for the food challenge; the overall time frame is not specified.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 10 to 55. Healthy volunteers may be eligible.
You may be able to join if
- Food allergy-only group
- Have a known history of food anaphylaxis to peanut, tree nut, egg, milk, or sesame confirmed by an allergist.
- Have had skin and blood food allergy testing to the food allergen in question within the past 6 months.
- No history of atopic dermatitis Food allergy plus atopic dermatitis group \- Meet the "food allergy only group" except this group must also have...
- Have a present diagnosis of atopic dermatitis by an allergist and/or dermatologist.
You likely can't join if
- People younger than age 10 or older than age 55
- Any active cardiovascular disease, cancer, pulmonary disease except well-controlled asthma, or other condition that would preclude an OFC otherwise.
- Any medication use that cannot be stopped temporarily for the OFC that would interfere with the OFC result.
- Any skin condition aside from atopic dermatitis per inclusion criteria groups that might impact the study, including such conditions as autoimmune...
- Any recent change (within 6 months) of starting or stopping a biologic medication, such as dupilumab, tezepelumab, or others that might interfere...
- Any past or present history of oral immunotherapy (OIT) for any food allergen.
See the full eligibility criteria
- Food allergy-only group
- Have a known history of food anaphylaxis to peanut, tree nut, egg, milk, or sesame confirmed by an allergist.
- Have had skin and blood food allergy testing to the food allergen in question within the past 6 months.
- No history of atopic dermatitis Food allergy plus atopic dermatitis group \- Meet the "food allergy only group" except this group must also have atopic dermatitis. Atopic dermatitis without food allergy
- Have a present diagnosis of atopic dermatitis by an allergist and/or dermatologist.
- Have no history of food allergy, past or present. Control Group \- No history of food allergy or atopic dermatitis, past or present.
- People younger than age 10 or older than age 55
- Any active cardiovascular disease, cancer, pulmonary disease except well-controlled asthma, or other condition that would preclude an OFC otherwise.
- Any medication use that cannot be stopped temporarily for the OFC that would interfere with the OFC result. Medications in this category include antihistamines (first or second generation) within 1 week.
- Any skin condition aside from atopic dermatitis per inclusion criteria groups that might impact the study, including such conditions as autoimmune skin conditions (such as psoriasis), congenital ichthyoses, hyper-IgE...
- Any recent change (within 6 months) of starting or stopping a biologic medication, such as dupilumab, tezepelumab, or others that might interfere with atopic dermatitis or food allergy.
- Any past or present history of oral immunotherapy (OIT) for any food allergen.
- Pregnancy - females of childbearing age will be asked and self-report pregnancy status.
The study team makes the final eligibility decision.
Where it is enrolling
- Ann Arbor, Michigan, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 10 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Ann Arbor, Michigan, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.