Metabolic Syndrome study: Impedancemetry
Official title Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients
ClinicalTrials.gov ID: NCT06360302
What this study is testing
- What it's testing
- The study aims to find if specific blood tests during exercise can better detect muscle problems caused by insulin resistance.
- Who it's for
- The study is looking for people with chronic kidney disease on dialysis, people with metabolic syndrome, and healthy volunteers.
- What's involved
- Participants will perform an exercise test while researchers take blood samples at different intensity levels to check for metabolic changes.
- Time commitment
- The study involves a single visit for the exercise test and blood draws.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 75. Healthy volunteers may be eligible.
You may be able to join if
- Postmenopausal women aged 40 to 75 or men aged 40 to 75
- No chronic disease or treatment
- BMI \<30 kg/m², or
- Fasting blood glucose \< 1.10 g/dL Group 2: metabolic syndrome patients
- Postmenopausal women aged 40 to 75 or men aged 40 to 75
You likely can't join if
- Non-stabilized pathology incompatible with physical exercise
- Ongoing exercise retraining program
- Nutritional supplementation in the 4 weeks preceding the study (antioxidants, vitamins, etc.)
- Treatment influencing mitochondrial function (metformin, statin, etc.)
- Failure to obtain written informed consent after a period of reflection
- Subject not affiliated to a social security scheme, or not benefiting from such a scheme.
See the full eligibility criteria
- Postmenopausal women aged 40 to 75 or men aged 40 to 75
- No chronic disease or treatment
- BMI \<30 kg/m², or
- Fasting blood glucose \< 1.10 g/dL Group 2: metabolic syndrome patients
- Postmenopausal women aged 40 to 75 or men aged 40 to 75
- Metabolic syndrome as defined by the International Diabetes Federation (IDF 2006)5
- BMI \ 80 cm for women and \>94 cm for men
- Insulin resistance defined by HOMA-IR\>2.4 Group 3: CKD dialysis patients
- Non-diabetics
- Postmenopausal women aged 40 to 75 and men aged 40 to 75
- BMI \<30 kg/m².
- Chronic kidney disease patients on dialysis - stable on HD for more than 3 months Patients and healthy people will be matched on age (+/-3 years) and sex
- Non-stabilized pathology incompatible with physical exercise
- Ongoing exercise retraining program
- Nutritional supplementation in the 4 weeks preceding the study (antioxidants, vitamins, etc.)
- Treatment influencing mitochondrial function (metformin, statin, etc.)
- Failure to obtain written informed consent after a period of reflection
- Subject not affiliated to a social security scheme, or not benefiting from such a scheme.
- Person protected by law (under guardianship or curatorship)
- Patient deprived of liberty
- Diabetic patient
- Family dyslipidemia
- Participants who have reached the maximum amount of compensation for their participation in research projects
- Person under psychiatric care
- Person participating in another research project with an exclusion period still in progress.
- Mentally handicapped, dementia, illiterate, language barrier with inability to understand study purpose and methodology
The study team makes the final eligibility decision.
Where it is enrolling
- Montpellier, France
Compensation & support
This study's listing mentions compensation or reimbursement.
No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team, so confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Montpellier, France. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.