Dysequilibrium Syndrome study: Urea in the dialysate
Official title Adding Urea to the Final Dialysis Fluid
ClinicalTrials.gov ID: NCT06366230
What this study is testing
What is Urea in the dialysate (Ure-Na)?
An investigational dialysis additive being studied as a potential treatment for dialysis disequilibrium syndrome. is designed to help maintain serum osmolality by adding urea to the dialysate during early dialysis sessions.
Also referred to as Ure-Na.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether adding urea to the dialysis fluid helps prevent a condition called disequilibrium syndrome. It looks at how this change affects blood levels during treatment.
- Who it's for
- You may be able to join if you have end-stage renal disease and need dialysis for high potassium or acid levels.
- What's involved
- You would receive dialysis with a special fluid that includes urea. The team would check your blood levels to see how your body reacts.
- Time commitment
- The study involves specific dialysis sessions and blood tests to monitor your health.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Serum Urea \> 120
- Serum Potassium \> 5.5 or serum CO2 \< 15 or need for aggressive dialysis due to toxic ingestion
- need for dialysis
You likely can't join if
- Pediatric
- need for CRRT
The study team makes the final eligibility decision.
Where it is enrolling
- San Francisco, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at San Francisco, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.