Chronic Obstructive Pulmonary Disease study: Air cleaner
Official title Multi-Center Clean Air Randomized Controlled Trial in COPD
ClinicalTrials.gov ID: NCT06376994
What this study is testing
- What it's testing
- The study will see whether using an air cleaner in the home reduces COPD flare‑ups and improves quality of life and breathing function.
- Who it's for
- Adults who have been diagnosed with chronic obstructive pulmonary disease (COPD).
- What's involved
- Participants will use an air cleaner at home and attend study visits for check‑ups and tests. A sham (inactive) cleaner will be used for comparison.
- Time commitment
- The trial lasts several months, with regular visits to the clinic for monitoring and data collection.
- Phase 3: a large, late-stage study
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- Age ≥ 40 years.
- Self-report of physician diagnosis of COPD.
- Spirometry confirmed airway obstruction (post-bronchodilator spirometry of forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) \<...
- Tobacco exposure ≥ 10 pack-years. This refers to regular cigarette tobacco consumption.
- Self-reported former smoker of at least 6 months' duration. This does not include e-cigarette use.
You likely can't join if
- Living in a location other than home (e.g., long-term care facility, nursing home)
- Other chronic lung diseases, except asthma
- Condition with less than a year of life expectancy (e.g., metastatic cancer) or in hospice
- Spends \>2 months per year in location other than home; or plans to change residence in the next 12 months
- Pregnant or breastfeeding
- Current air cleaner use in the home (\ If the individual is willing to discontinue use of the personal air cleaner, this person can be eligible if...
See the full eligibility criteria
- Age ≥ 40 years.
- Self-report of physician diagnosis of COPD.
- Spirometry confirmed airway obstruction (post-bronchodilator spirometry of forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) \< 0.7) as defined by the Global Initiative for Obstructive Lung Disease...
- Tobacco exposure ≥ 10 pack-years. This refers to regular cigarette tobacco consumption.
- Self-reported former smoker of at least 6 months' duration. This does not include e-cigarette use.
- COPD Assessment Test (CAT) score ≥ 10, Modified Medical Research Council dyspnea scale (mMRC) ≥ 2, or history of moderate or severe exacerbation in the past 12 months (as defined by history of receiving a course of...
- Living in a location other than home (e.g., long-term care facility, nursing home)
- Other chronic lung diseases, except asthma
- Condition with less than a year of life expectancy (e.g., metastatic cancer) or in hospice
- Spends \>2 months per year in location other than home; or plans to change residence in the next 12 months
- Pregnant or breastfeeding
- Current air cleaner use in the home (\ If the individual is willing to discontinue use of the personal air cleaner, this person can be eligible if all other eligibility has been met)
- Inability to bring air cleaners (about 15 pounds each) into home, either by self, friend, or relative
- Deemed by the study investigator to be unable to complete study protocol, including likely lack of internet connectivity
- Participating in another treatment clinical trial
The study team makes the final eligibility decision.
Where it is enrolling
- Birmingham, Alabama, United States
- Los Angeles, California, United States
- Iowa City, Iowa, United States
- Baltimore, Maryland, United States
- Salisbury, Maryland, United States
- Boston, Massachusetts, United States
- Ann Arbor, Michigan, United States
- Lebanon, New Hampshire, United States
- Cleveland, Ohio, United States
- West Reading, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Birmingham, Alabama, United States; Los Angeles, California, United States; Iowa City, Iowa, United States; Baltimore, Maryland, United States; Salisbury, Maryland, United States; Boston, Massachusetts, United States and 4 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.