Trapeziometacarpal Osteoarthritis study: Saline Solution vs Triamcinolone Acetonide
Official title Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)
ClinicalTrials.gov ID: NCT06401317
What this study is testing
What is Saline Solution (0.9% NaCl)?
An investigational intra‑articular injection being studied for treating trapeziometacarpal osteoarthritis.
Also referred to as Saline solution.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study compares how well saline versus steroid injections reduce pain and improve hand function in thumb arthritis.
- Who it's for
- Adults with trapeziometacarpal (thumb) osteoarthritis.
- What's involved
- Participants receive one injection of either saline or a steroid, and neither the patient nor the doctor knows which one is given. They will be followed up with visits and tests to measure pain and hand use.
- Time commitment
- The study lasts about a few weeks to months, with scheduled visits for injections and follow‑up assessments.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- aged ≥18 years;
- diagnosis of TMO was confirmed by X-ray interpreted by a radiologist;
- suffering from pain at the base of the thumb;
- the attending physician deems that an intra-articular corticosteroid injection would be beneficial, rather than opting for other types of...
- can read, understand and answer in either French or English.
You likely can't join if
- having received one or more corticosteroid injections in the last 3 months or surgery on the affected thumb;
- suffering from painful thumb caused by a trauma (e.g., fracture, sprain), rheumatoid arthritis, or De Quervain's tendonitis; and
- being pregnant or breastfeeding; and
- known allergies to any components of the solutions (triamcinolone acetonide, benzyl alcohol, carboxymethylcellulose sodium, hydrochloric acid...
The study team makes the final eligibility decision.
Where it is enrolling
- Montreal, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Montreal, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.