PCOS study: Metformin vs Fish Oil and Metformin
Official title Fish Oil, Metformin and Heart Health in PCOS
ClinicalTrials.gov ID: NCT06424860
What this study is testing
What is Metformin?
Metformin is an investigational oral medication being studied as part of a combination therapy with fish oil for women with PCOS. Metformin is designed to improve insulin sensitivity and reduce glucose production by the liver.
Also referred to as Glucophage.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study looks to see if adding fish oil to metformin improves heart health, blood fats, and sugar control.
- Who it's for
- Women with Polycystic Ovary Syndrome (PCOS), including some who also have Type 2 Diabetes.
- What's involved
- Participants will take fish oil supplements along with their usual metformin treatment and undergo health checks.
- Time commitment
- The source text does not specify the study duration or visit schedule.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 25 to 45, women only
You may be able to join if
- diagnosis of PCOS
- overweight-obese (BMI \>25 kg/m2)
- elevated fasting plasma TG (\>150 mg/dL)
- and/or apoB48-remnant cholesterol lipoproteins (\>20 ug/ml)
- impaired insulin sensitivity (glucose 100-125 mg/dL and/or insulin \>15 (uM/ml), and may be diagnosed with T2D (blood glucose \>126 mg/dL).
You likely can't join if
- -pregnancy, lactation
The study team makes the final eligibility decision.
Where it is enrolling
- Edmonton, Alberta, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 25 years to 45 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Edmonton, Alberta, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.