Recruiting at 1 site Phase 2 Cannabis Use Disorder

Cannabis Use Disorder study: Dronabinol Pill

Official title Effects of THC on Alcohol Consumption and Neural Correlates of Reward

ClinicalTrials.gov ID: NCT06446479

What this study is testing

What is Dronabinol Pill?

An investigational oral medication being studied as a potential treatment for Cannabis Use Disorder. It is designed to activate cannabinoid receptors in the brain, mimicking the effects of THC.

Also referred to as THC, Marinol.

Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The study aims to see how a high dose of THC affects alcohol consumption patterns and brain reward signals.
Who it's for
Adults who have a cannabis use disorder.
What's involved
Participants will receive either oral THC or a placebo, undergo brain scans, and be allowed to drink alcohol in a controlled setting while their use is monitored.
  • Phase 2: a mid-size study of how well it works
  • You might receive a placebo (an inactive treatment) instead of the study drug.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 21 to 40. Healthy volunteers may be eligible.

You may be able to join if

  • Drink alcohol
  • Use cannabis
  • Contact site for additional details

You likely can't join if

  • MRI contraindications (implanted metal, weight \> 315 lb, etc.).
  • Contact site for additional details

The study team makes the final eligibility decision.

Where it is enrolling

  • Aurora, Colorado, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 21 years to 40 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

This study is enrolling now at Aurora, Colorado, United States. Enter your location above to see the nearest enrolling site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.