Clinical trial for Depression
Official title Antidepressant Adherence for Depressed Adults in Primary Care
ClinicalTrials.gov ID: NCT06496646
What this study is testing
- What it's testing
- This study is testing whether new methods can help people with depression take their medicine as prescribed and feel better.
- Who it's for
- You may be able to join if you are an adult with depression and take medication for it.
- What's involved
- You will try different ways to remember and take your medicine, and share how you feel about your mood.
- Time commitment
- The study lasts a few months and includes regular check‑ins to track your medication use and mood.
- Time commitment: about 12 weeks
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 64
You may be able to join if
- Penn Medicine primary care outpatients
- Clinical diagnosis of major depressive disorder
- A score of 10+ on the Patient Health Questionnaire 9 (PHQ-9)
- Age 21 to 64 years at the time of study entry
- Prescribed an antidepressant by their primary care clinician
You likely can't join if
- Treated with antidepressants in the past 90 days
- Pregnant or breastfeeding
- An active substance use disorder other than nicotine
- A lifetime history of treatment for bipolar disorder or schizophrenia
- Hospital admission or emergency department visit for suicidal symptoms in the past year
- Lack capacity to provide informed consent
See the full eligibility criteria
- Penn Medicine primary care outpatients
- Clinical diagnosis of major depressive disorder
- A score of 10+ on the Patient Health Questionnaire 9 (PHQ-9)
- Age 21 to 64 years at the time of study entry
- Prescribed an antidepressant by their primary care clinician
- Express interest in taking antidepressant medication
- Own a cell phone
- Capable of using the electronic pill bottle
- English-speaking
- Treated with antidepressants in the past 90 days
- Pregnant or breastfeeding
- An active substance use disorder other than nicotine
- A lifetime history of treatment for bipolar disorder or schizophrenia
- Hospital admission or emergency department visit for suicidal symptoms in the past year
- Lack capacity to provide informed consent
- Using antidepressant more than 10 days at baseline assessment
The study team makes the final eligibility decision.
Where it is enrolling
- Philadelphia, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 12 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 64 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Philadelphia, Pennsylvania, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.