Recruiting at 2 sites No phase Nicotine Dependence

Nicotine Dependence study: Flavor

Official title Abuse Liability and Appeal of Oral Nicotine Products

ClinicalTrials.gov ID: NCT06506162

What this study is testing

What it's testing
The study looks at whether mint or fruit flavors and 2 mg or 4 mg nicotine levels make these products more appealing and more likely to be used, especially by people who already use e‑cigarettes.
Who it's for
It is looking for people aged 21‑25 who exclusively use e‑cigarettes, including about 20 % who identify as sexual or gender minorities.
What's involved
Participants will take part in a virtual session where they try different gum and pouch products, rate how appealing they are, and then use their preferred mint and fruit products in a follow‑up session that measures how much they like them, how much they use them, and whether they feel relief from nicotine cravings.
Time commitment
The study lasts about one day of virtual visits, with a second short session a few days later to track use of the chosen products.
  • Which group you join is decided by chance.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 21 to 25. Healthy volunteers may be eligible.

You may be able to join if

  • aged 21-25 years
  • current exclusive EC user (defined as at least weekly use over the past 3 months) and recent nicotine use confirmed by positive urine test (\>1...
  • not currently using another tobacco/nicotine product (defined as no use in the past 6 months)
  • have never used any ONP (medicinal or nonmedicinal)
  • willing to try study provided ONPs.

You likely can't join if

  • recent COVID-19+ (positive test in the past 30 days)
  • a recent COVID-19 hospitalization (past 3 months)
  • unstable or significant psychiatric conditions (past and stable conditions allowed)
  • history of cardiac event or distress within the past 3 months
  • currently pregnant (based on urine pregnancy test), planning to become pregnant, or breastfeeding.

The study team makes the final eligibility decision.

Where it is enrolling

  • Los Angeles, California, United States

Compensation & support

A stipend or payment for your time may be offered.

No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.

Questions & answers

Do participants get paid in this trial?

This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team, so confirm the details with them.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 21 years to 25 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

This study is enrolling now at Los Angeles, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.