Locally Advanced or Metastatic Solid Tumors study: XB010 vs Pembrolizumab
Official title Study of XB010 in Subjects With Solid Tumors
ClinicalTrials.gov ID: NCT06545331
What this study is testing
What is XB010?
XB010 is an investigational medicine being studied as a potential treatment for certain types of solid tumors.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to determine if XB010 is safe, how it behaves in the body, and whether it shows early signs of fighting cancer.
- Who it's for
- Adults with advanced or metastatic solid tumors who have no other treatment options.
- What's involved
- Participants receive XB010, sometimes with pembrolizumab, and undergo blood tests and scans to monitor safety and tumor response.
- Time commitment
- The study lasts several weeks to months, with regular clinic visits and tests.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age 18 years or older on the day of consent.
- Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-1.
- Adequate organ and marrow function.
- Cytologically or histologically and radiologically confirmed solid tumor that is inoperable, locally advanced, metastatic, or recurrent.
- The Cohort Expansion stage will enroll people with multiple tumor types (non-small cell lung cancer, hormone-receptor-positive breast cancer, head...
See the full eligibility criteria
- Age 18 years or older on the day of consent.
- Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-1.
- Adequate organ and marrow function.
- Cytologically or histologically and radiologically confirmed solid tumor that is inoperable, locally advanced, metastatic, or recurrent.
- The Cohort Expansion stage will enroll people with multiple tumor types (non-small cell lung cancer, hormone-receptor-positive breast cancer, head and neck cancer, esophageal squamous cell, triple-negative breast...
- Capable of understanding and complying with the protocol requirements and must have signed the informed consent document.
The study team makes the final eligibility decision.
Where it is enrolling
- Irvine, California, United States
- Los Angeles, California, United States
- Orlando, Florida, United States
- Atlanta, Georgia, United States
- Chicago, Illinois, United States
- St Louis, Missouri, United States
- The Bronx, New York, United States
- Oklahoma City, Oklahoma, United States
- Nashville, Tennessee, United States
- Austin, Texas, United States
- Dallas, Texas, United States
- Houston, Texas, United States
- Fairfax, Virginia, United States
- Leicester, United Kingdom
- London, United Kingdom
- Manchester, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Irvine, California, United States; Los Angeles, California, United States; Orlando, Florida, United States; Atlanta, Georgia, United States; Chicago, Illinois, United States; St Louis, Missouri, United States and 10 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.