Smoking Cessation study: Nicotine Metabolite Ratio
Official title Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)
ClinicalTrials.gov ID: NCT06556238
What this study is testing
- What it's testing
- The study wants to find out if using the Nicotine Metabolite Ratio to pick a medication helps people quit smoking and whether this approach is acceptable and doable.
- Who it's for
- Alaska Native or American Indian adults who currently smoke.
- What's involved
- Participants will have a simple test that measures how their body processes nicotine, then receive a smoking‑cessation drug chosen based on that result, plus follow‑up visits and questionnaires.
- Time commitment
- The pilot runs for several months and includes multiple clinic visits during that time.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- (Patients)
- Alaska Native or American Indian person by self-report
- eligible for or already receiving services at Southcentral Foundation (SCF)
- age 18 years or older
- daily smoking in the past 30-days
You likely can't join if
- (Patients)
- Participated in the prior study phase
- participated in a cessation program during the past 3 months
- their provider has not approved varenicline in their referral to the Quit Tobacco Program
- has history of serious hypersensitivity or skin reactions to varenicline
- has bleeding disorder or is currently receiving cancer treatment
See the full eligibility criteria
- (Patients)
- Alaska Native or American Indian person by self-report
- eligible for or already receiving services at Southcentral Foundation (SCF)
- age 18 years or older
- daily smoking in the past 30-days
- if other nicotine or tobacco products are used, cigarettes are main product used
- planning to schedule an appointment with the Quit Tobacco Program to seek smoking cessation treatment in the next 30 days
- willing to make a quit attempt within 30 days of enrollment in the Quit Tobacco Program
- willing to have a blood test to inform their treatment
- willing to try a pharmacologic treatment
- willing to provide a saliva sample
- has phone service
- has access to broadband internet on mobile phone at home, work, or other location
- has an Android or iPhone mobile phone compatible with the Smokerlyzer app (Staff) \- Staff participants of qualitative interviews to assess acceptability and feasibility of the intervention must be a health care...
- (Patients)
- Participated in the prior study phase
- participated in a cessation program during the past 3 months
- their provider has not approved varenicline in their referral to the Quit Tobacco Program
- has history of serious hypersensitivity or skin reactions to varenicline
- has bleeding disorder or is currently receiving cancer treatment
- questionable capacity or impaired decision-making capacity
The study team makes the final eligibility decision.
Where it is enrolling
- Anchorage, Alaska, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Anchorage, Alaska, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.