Clinical trial for Tobacco Use Disorder
Official title Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes
ClinicalTrials.gov ID: NCT06614504
What this study is testing
- What it's testing
- The study wants to see if cigarettes with very low nicotine reduce how much people smoke and how dependent they feel, and whether the nicotine level in e‑cigarettes changes that effect.
- Who it's for
- Adults who regularly smoke cigarettes and also use e‑cigarettes.
- What's involved
- Participants will receive either normal‑nicotine or very‑low‑nicotine cigarettes and either high‑nicotine or low‑nicotine e‑cigarettes for 12 weeks. They will attend clinic visits for instructions, give samples, and have tests to measure smoking, dependence, and exposure to harmful chemicals.
- Time commitment
- The study lasts 12 weeks and requires several clinic visits during that period.
- Phase 2: a mid-size study of how well it works
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 and older. Healthy volunteers may be eligible.
You may be able to join if
- Regular use of tobacco
- 21 year of age or older
- Speak, comprehend and read English well enough to complete study procedures
You likely can't join if
- Pregnant, trying to become pregnant, or nursing
- Under the age of 21
- Health conditions that could undermine ability to complete the study
The study team makes the final eligibility decision.
Where it is enrolling
- Providence, Rhode Island, United States
- Burlington, Vermont, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Providence, Rhode Island, United States; Burlington, Vermont, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.