Renal Failure study: CoQ10
Official title Prevent Cardiac Surgery Associated AKI Trial
ClinicalTrials.gov ID: NCT06620523
What this study is testing
What is CoQ10 1200 mg orally with Glutathione 1000 mg orally?
An investigational oral supplement being studied to prevent acute kidney injury after cardiac surgery.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether giving CoQ10 and glutathione before and after heart surgery helps protect the kidneys. It compares this to a pretend treatment.
- Who it's for
- You may join if you are scheduled for heart surgery and have kidney or heart disease.
- What's involved
- You will take a pill with CoQ10 and glutathione each day, starting the day before surgery. You will have blood and urine samples taken and doctors will watch for side effects.
- Time commitment
- The study lasts about one week in the hospital, with daily visits for blood and urine tests.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Adult 18-70 years of age
- Undergoing elective CPB (Cardiopulmonary Bypass) surgery
- Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min
You likely can't join if
- GFR (Glomerular Filtration Rate) \<45 ml/min
- Solitary kidney
- Status post-kidney transplant
- Pregnant women
- Allergy to CoQ10
- Allergy to Glutathione
See the full eligibility criteria
- Adult 18-70 years of age
- Undergoing elective CPB (Cardiopulmonary Bypass) surgery
- Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min
- GFR (Glomerular Filtration Rate) \<45 ml/min
- Solitary kidney
- Status post-kidney transplant
- Pregnant women
- Allergy to CoQ10
- Allergy to Glutathione
- Allergy to Cellulose
The study team makes the final eligibility decision.
Where it is enrolling
- Washington D.C., District of Columbia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Washington D.C., District of Columbia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.