Barrett Esophagus study: EsoCheck vs EsoGuard
Official title Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
ClinicalTrials.gov ID: NCT06687603
What this study is testing
- What it's testing
- This study is testing whether the EsoCheck capsule can spot Barrett’s esophagus. It also checks if the test works well for screening.
- Who it's for
- You may be able to join if you are an adult who has never had long‑term reflux symptoms and you are willing to try a new test.
- What's involved
- You will fill out a questionnaire, swallow a small capsule that inflates in your stomach, and then have a lab test on the capsule’s sample. You will also have a normal upper endoscopy as part of your care.
- Time commitment
- The study lasts about one day, with a follow‑up endoscopy scheduled soon after the capsule test.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older. Healthy volunteers may be eligible.
You may be able to join if
- Adults \> age 50, who also have two or more added risk factors for BE from the set of: central obesity (waist size \> 35 inches for women and \> 40...
- people must have the ability to understand and the willingness to sign a written informed consent document.
- people must have the ability to understand and the willingness to sign a written informed consent document.
You likely can't join if
- History of prior EGD procedure in past ten years
- Inability to provide written informed consent
- History of weekly of more frequent heartburn or regurgitation for five or more years
- On anti-coagulant drug(s) that cannot be temporarily discontinued or coagulopathy with INR \> 1.5
- Known history of esophageal varices or esophageal stricture
- Any contraindication, as deemed in Investigator's medical judgment, to undergoing the EsoCheck procedure, undergoing the EGD procedure, and/or having...
See the full eligibility criteria
- Adults \> age 50, who also have two or more added risk factors for BE from the set of: central obesity (waist size \> 35 inches for women and \> 40 inches for men), current smoker or smoking history \> 10 pack years...
- people must have the ability to understand and the willingness to sign a written informed consent document.
- people must have the ability to understand and the willingness to sign a written informed consent document.
- History of prior EGD procedure in past ten years
- Inability to provide written informed consent
- History of weekly of more frequent heartburn or regurgitation for five or more years
- On anti-coagulant drug(s) that cannot be temporarily discontinued or coagulopathy with INR \> 1.5
- Known history of esophageal varices or esophageal stricture
- Any contraindication, as deemed in Investigator's medical judgment, to undergoing the EsoCheck procedure, undergoing the EGD procedure, and/or having biopsies taken, including but not limited to due to comorbidities...
- History of difficulty swallowing (dysphagia) or painful swallowing (odynophagia), including swallowing pills
- Oropharyngeal tumor
- History of esophageal or gastric surgery, with exception of uncomplicated surgical fundoplication procedure
The study team makes the final eligibility decision.
Where it is enrolling
- Aurora, Colorado, United States
- Baltimore, Maryland, United States
- Chapel Hill, North Carolina, United States
- Cleveland, Ohio, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Aurora, Colorado, United States; Baltimore, Maryland, United States; Chapel Hill, North Carolina, United States; Cleveland, Ohio, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.