Clinical trial for Major Depressive Diorder
Official title qEEG Brain Signature of Depression & Neuromodulation-induced Recovery
ClinicalTrials.gov ID: NCT06719427
What this study is testing
- What it's testing
- The study wants to find out if a new quick brain‑wave test can show how a magnetic brain treatment (rTMS) changes brain function and whether those changes relate to feeling better or getting worse again.
- Who it's for
- Adults who have major depressive disorder and are receiving rTMS treatment.
- What's involved
- Participants will have a short, dry brain‑wave test before, during, and up to 12 months after their rTMS sessions. The test records electrical activity for about 15 minutes without gel or long electrode setup.
- Time commitment
- The study lasts up to 12 months, with brain‑wave tests scheduled before treatment, during the course of treatment, and at follow‑up visits after treatment ends.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- A diagnosis of Depression based on Diagnostic and Statistical Manual (DSM) 5.0 criteria.
- Receiving a neuromodulation (rTMS) treatment for depression at the HCN
- Physically healthy
- Age 18-80, inclusive.
- Able to provide informed consent and comply with the study protocol.
You likely can't join if
- Moderate substance use disorder or greater severity based on DSM 5.0 criteria and confirmed by a study MD on clinical assessment.
- Mild and major comorbid medical conditions (as determined by investigators - e.g., neurological diseases, uncontrolled hypertension or diabetes...
- A major comorbid psychiatric disorder (as determined by investigators - e.g., schizophrenia or bipolar disorder) and/or psychosis at the time of...
- History of seizure disorder
- Pregnant
See the full eligibility criteria
- A diagnosis of Depression based on Diagnostic and Statistical Manual (DSM) 5.0 criteria.
- Receiving a neuromodulation (rTMS) treatment for depression at the HCN
- Physically healthy
- Age 18-80, inclusive.
- Able to provide informed consent and comply with the study protocol.
- Patients will not be excluded solely based on communication (i.e., non-English speaking) unless they have
- Moderate substance use disorder or greater severity based on DSM 5.0 criteria and confirmed by a study MD on clinical assessment.
- Mild and major comorbid medical conditions (as determined by investigators - e.g., neurological diseases, uncontrolled hypertension or diabetes, malignancy)
- A major comorbid psychiatric disorder (as determined by investigators - e.g., schizophrenia or bipolar disorder) and/or psychosis at the time of study enrollment.
- History of seizure disorder
- Pregnant
The study team makes the final eligibility decision.
Where it is enrolling
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Toronto, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.