Trial comparing treatments for Infertility (IVF Patients)
Official title Cleavage-stage Versus Blastocyst-stage Embryo Transfer in IVF Patients With Few Embryos
ClinicalTrials.gov ID: NCT06746129
What this study is testing
- What it's testing
- This study is testing whether an 8‑cell embryo transfer or a blastocyst transfer leads to better pregnancy results and satisfaction for people with few embryos.
- Who it's for
- You may be able to join if you are an IVF patient with five or fewer embryos and a doctor thinks you have a poor chance of success.
- What's involved
- You will be randomly assigned to have your embryos transferred at either the 8‑cell stage or the blastocyst stage. You will attend the usual IVF visits and follow the same care plan as other IVF patients.
- Time commitment
- The study lasts until the embryo transfer and the follow‑up check‑in after the transfer, usually a few weeks.
- Phase 3: a large, late-stage study
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 44, women only
You may be able to join if
- autologous IVF cycle
- ≤5 zygotes on day 1 of development
- Fresh embryo transfer
You likely can't join if
- Planned preimplantation genetic testing (PGT) of all embryos
- More than 2 previous IVF cycles
- History of recurrent pregnancy loss (≥3)
- Body mass index \>40
- Presence of uterine factor infertility
- Planned gestational carrier
See the full eligibility criteria
- autologous IVF cycle
- ≤5 zygotes on day 1 of development
- Fresh embryo transfer
- Planned preimplantation genetic testing (PGT) of all embryos
- More than 2 previous IVF cycles
- History of recurrent pregnancy loss (≥3)
- Body mass index \>40
- Presence of uterine factor infertility
- Planned gestational carrier
- Endometrial lining \<6mm measured on the day of trigger
- Lupron-only trigger, elevated progesterone in the fresh cycle (≥1.5ng/ml)
- Delayed fertilization (\>18 hours)
- Rescue intracytoplasmic sperm injection (following failed regular fertilization)
- Use of non-ejaculated sperm (testicular sperm extraction)
- Embryo transfer number outside American Society of Reproductive Medicine (ASRM) guidelines
- Cycle is converted to a cycle in which all embryos are frozen
The study team makes the final eligibility decision.
Where it is enrolling
- Boston, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 44 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Boston, Massachusetts, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.