Clinical trial for Tinnitus
Official title Low-intensity TUS for Sleep Disturbances in Patients With Chronic Tinnitus
ClinicalTrials.gov ID: NCT06776705
What this study is testing
- What it's testing
- The study will check whether the ultrasound is safe, doable, and can improve tinnitus severity, sleep quality, and thinking skills. It will also help plan a larger future trial.
- Who it's for
- People aged 60‑90 who have tinnitus, trouble sleeping, and are right‑handed.
- What's involved
- Participants will have a brain MRI, then receive either real or fake low‑intensity ultrasound for two weeks. Their sleep, tinnitus, cognition, and quality of life will be measured at the start, after two weeks, and again at four and six weeks.
- Time commitment
- The study lasts about six weeks, with a two‑week daily treatment period and clinic visits for assessments at weeks 0, 2, 4, and 6.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 85
You may be able to join if
- Chinese, right-handed, aged from 60 to 80 years.
- Chronic tinnitus is defined as tinnitus with a duration of at least 3 months.
- Sleep disturbances are defined as a Pittsburgh Sleep Quality Index (PSQI) total score above 5.
- No interference with independence in everyday activities.
You likely can't join if
- Diseases of ear canal and tympanic membrane checked by otoscopic examination.
- Previous diagnosis of Meniere's disease and acoustic neuromas.
- Past history of neurological or mental disorders.
- Physically frail affecting attendance to treatment sessions.
- Already attending regular treatments, such as cognitive behavioral therapy or music therapy.
- Taking a psychotropic or other medication known to affect hearing functions.
See the full eligibility criteria
- Chinese, right-handed, aged from 60 to 80 years.
- Chronic tinnitus is defined as tinnitus with a duration of at least 3 months. Depending on the justification, different time course definitions of chronic tinnitus are possible.
- Sleep disturbances are defined as a Pittsburgh Sleep Quality Index (PSQI) total score above 5.
- No interference with independence in everyday activities.
- Diseases of ear canal and tympanic membrane checked by otoscopic examination.
- Previous diagnosis of Meniere's disease and acoustic neuromas.
- Past history of neurological or mental disorders.
- Physically frail affecting attendance to treatment sessions.
- Already attending regular treatments, such as cognitive behavioral therapy or music therapy.
- Taking a psychotropic or other medication known to affect hearing functions.
- Significant communicative impairments.
The study team makes the final eligibility decision.
Where it is enrolling
- Hong Kong, Tai Po District, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Hong Kong, Tai Po District, Hong Kong. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.