Clinical trial for Papillary Thyroid Cancer
Official title A Clinical Study on the Benefits of Carbon Nanoparticles Injection Time in Patients With Thyroid Cancer.
ClinicalTrials.gov ID: NCT06791005
What this study is testing
What is Preoperative Injection of Carbon Nanoparticles?
This is an investigational injection of tiny carbon particles being studied to help doctors see the thyroid gland and nearby lymph nodes more clearly during surgery for papillary thyroid cancer. It is designed to be absorbed by the lymphatic system to highlight the location of lymph nodes and the tumor for better visualization during the operation.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study compares the effects of injecting carbon nanoparticles before surgery versus during surgery on how well the surgeon can find parathyroid glands and remove lymph nodes, and on complications after thyroid removal.
- Who it's for
- Adults diagnosed with papillary thyroid cancer who will have thyroid surgery.
- What's involved
- Participants will receive carbon nanoparticle injections at different times (before or during surgery) and will have their surgery and recovery monitored for complications and surgical success.
- Time commitment
- The study involves a single surgery and follow‑up visits over the postoperative period, lasting about a year from the time of surgery.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 16 to 80
You may be able to join if
- Preoperative pathological assessment indicated the presence of thyroid cancer with a maximum diameter of less than 4 cm.
- Postoperative pathological evaluation confirmed bilateral thyroid cancer or lateral lymph node metastasis.
- Vocal cord examination conducted one week prior to surgery revealed no abnormalities.
- The patient had no history of prior thyroid surgery and required a total thyroidectomy.
- Blood pressure was stably controlled.
You likely can't join if
- Prior to enrollment, the patient had received radiotherapy, chemotherapy, or isotope therapy.
- A documented history of thyroid surgery.
- Age under 16 years.
- Known allergies to the medications under investigation or an inability to tolerate surgical intervention.
- Presence of a retrosternal thyroid tumor.
- Tumor invasion of the parathyroid glands and/or the recurrent laryngeal nerve during surgical procedures.
See the full eligibility criteria
- Preoperative pathological assessment indicated the presence of thyroid cancer with a maximum diameter of less than 4 cm.
- Postoperative pathological evaluation confirmed bilateral thyroid cancer or lateral lymph node metastasis.
- Vocal cord examination conducted one week prior to surgery revealed no abnormalities.
- The patient had no history of prior thyroid surgery and required a total thyroidectomy.
- Blood pressure was stably controlled.
- The patient regained consciousness and was able to communicate normally.
- Prior to enrollment, the patient had received radiotherapy, chemotherapy, or isotope therapy.
- A documented history of thyroid surgery.
- Age under 16 years.
- Known allergies to the medications under investigation or an inability to tolerate surgical intervention.
- Presence of a retrosternal thyroid tumor.
- Tumor invasion of the parathyroid glands and/or the recurrent laryngeal nerve during surgical procedures.
- Postoperative pathology suggestive of medullary carcinoma or undifferentiated carcinoma.
- Development of a postoperative tracheal fistula.
The study team makes the final eligibility decision.
Where it is enrolling
- Xi'an, Shaanxi, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 16 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Xi'an, Shaanxi, China. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.