Vitamin D Insufficiency study: DELTIUS
Official title 25(OH)-Vitamin D and Its Association With Structural and Functional Parameters in Hospitalized Patients With Neurological Diseases
ClinicalTrials.gov ID: NCT06791044
What this study is testing
- What it's testing
- The study wants to see how common low vitamin D is in these patients and whether giving vitamin D changes bone health, muscle strength, walking speed, and pain.
- Who it's for
- Hospitalized adults with neurological conditions that cause motor problems, such as stroke, spinal cord injury, or traumatic brain injury.
- What's involved
- Participants will have blood tests for vitamin D and other markers, bone density scans, and tests of strength and walking speed. Some will receive high‑dose vitamin D weekly for 8 weeks, others a lower dose for 4 weeks then a maintenance dose for 4 more weeks, while a small control group will not get the supplement.
- Time commitment
- The study lasts about 2 years, with regular visits for blood draws, scans, and physical tests, plus follow‑up after the supplement period.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 85. Healthy volunteers may be eligible.
You may be able to join if
- populations with neurological disorders
- healthy volunteers (controls)
You likely can't join if
- are legally or mentally incapable of comprehending and consenting to participate in the study
- have a history of or exhibit indicators of metabolic bone disease, including the following: Hypoparathyroidism, primary hyperparathyroidism, recent...
- grade 3 or 4 pressure ulcers present;
- has undergone treatment with pharmacological agents influencing bone metabolism prior to the initial bone density assessment, including the...
- Thyroid drugs are permissible only if the dosage has remained consistent for the preceding six weeks and TSH levels are within the normal range.
- Corticosteroid medication exceeding 7.5 mg of prednisone orally per day for a duration exceeding one month within the past six months.
See the full eligibility criteria
- populations with neurological disorders
- healthy volunteers (controls)
- are legally or mentally incapable of comprehending and consenting to participate in the study
- have a history of or exhibit indicators of metabolic bone disease, including the following: Hypoparathyroidism, primary hyperparathyroidism, recent hyperthyroidism (within the last six months), Paget's disease of bone;
- grade 3 or 4 pressure ulcers present;
- has undergone treatment with pharmacological agents influencing bone metabolism prior to the initial bone density assessment, including the following: bisphosphonates in the year prior to the bone density assessment
- Thyroid drugs are permissible only if the dosage has remained consistent for the preceding six weeks and TSH levels are within the normal range.
- Corticosteroid medication exceeding 7.5 mg of prednisone orally per day for a duration exceeding one month within the past six months.
- Immunosuppressant therapy within the past year;
- Vitamin A therapy above 10,000 IU per day or Vitamin D exceeding 5,000 IU per day.
- Participants are prohibited from consuming additional vitamin D supplements exceeding 400 IU per day or traveling to regions with heightened sunshine exposure during the trial.
The study team makes the final eligibility decision.
Where it is enrolling
- Nea Liosia, Athens, Greece
- Athens, Attica, Greece
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 85 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Nea Liosia, Athens, Greece; Athens, Attica, Greece. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.