Localized Prostate Cancer study: SBRT
Official title Is Adaptive SBRT for Prostate vs Image-guided Radiotherapy a True Evolution (ASPIRE)
ClinicalTrials.gov ID: NCT06825091
What this study is testing
- What it's testing
- The study wants to see if adaptive SBRT can improve urinary symptoms while still controlling the cancer as well as standard SBRT.
- Who it's for
- Men over 18 with localized prostate cancer, good overall health (ECOG 0‑1), and eligible for SBRT.
- What's involved
- Participants are randomly assigned to receive either adaptive SBRT or standard SBRT, delivered in 5 or 7 treatment sessions. The protocol may include a rectal spacer and hormone therapy as needed, and requires planning scans and follow‑up tests.
- Time commitment
- Treatment lasts about 5‑7 sessions over a few weeks, with scheduled clinic visits for planning, treatment, and follow‑up.
- Phase 3: a large, late-stage study
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, men only
You may be able to join if
- Age \>18 years
- Histologic diagnosis of prostate adenocarcinoma
- Localized prostate cancer
- Low risk, intermediate risk, or high risk allowed
- Patient planned for prostate SBRT
You likely can't join if
- Planned for elective nodal irradiation
- Contraindications to radiotherapy
- Patients with bilateral hip replacements, as they are ineligible for adaptive treatments at present time (either MR-guided or CT-guided)
The study team makes the final eligibility decision.
Where it is enrolling
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Toronto, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.