Clinical trial for Obsessive Compulsive Disorder (OCD)
Official title Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder
ClinicalTrials.gov ID: NCT06834217
What this study is testing
- What it's testing
- The study wants to see if people with OCD have trouble learning that a scary cue is actually safe, and whether a non‑invasive brain‑stimulation method can improve that learning.
- Who it's for
- Adults who have been diagnosed with obsessive‑compulsive disorder.
- What's involved
- Participants will receive a mild electrical stimulation to the scalp while learning to ignore scary cues, and will have brain scans and safety‑learning tests before and after the stimulation.
- Time commitment
- The study lasts a few weeks, with several visits for stimulation sessions, safety‑learning tests, and brain scans.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70. Healthy volunteers may be eligible.
You may be able to join if
- 18 years of age or older
- speak English fluently, and
- able to provide written and verbal informed consent.
- meet criteria for OCD as determined by structured clinical interview
- exhibit significant current symptoms of OCD
You likely can't join if
- active severe substance use disorder(s)
- acute suicidality
- history of bipolar or psychotic disorder(s)
- significant developmental disabilities
- loss of consciousness \> 10 minutes
- history of traumatic brain injury
See the full eligibility criteria
- 18 years of age or older
- speak English fluently, and
- able to provide written and verbal informed consent.
- meet criteria for OCD as determined by structured clinical interview
- exhibit significant current symptoms of OCD
- report duration of OCD symptoms of at least 1-year
- OCD symptoms are primary or co-primary relative to other psychiatric diagnoses
- stable psychiatric treatment (≥8-weeks) or no active treatment.
- exhibit significant current symptoms of OCD as determined by the Dimensional Obsessive-Compulsive Scale (DOCS) (≥18).
- active severe substance use disorder(s)
- acute suicidality
- history of bipolar or psychotic disorder(s)
- significant developmental disabilities
- loss of consciousness \> 10 minutes
- history of traumatic brain injury
- major neurological disease
- a positive pregnancy test
- other brain stimulation or magnetic resonance imaging contraindications
- new psychological treatment within the past 8 weeks
- daily anxiolytic medication use (e.g., benzodiazepine).
- meet current criteria for a psychiatric disorder as determined by structured clinical interview
- active-psychotropic medications.
The study team makes the final eligibility decision.
Where it is enrolling
- New Haven, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at New Haven, Connecticut, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.