Generalized Anxiety Disorder study: ABBV-932 vs Antidepressant Therapy
Official title Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
ClinicalTrials.gov ID: NCT06846320
What this study is testing
What is ABBV-932?
An investigational oral capsule being studied as an adjunctive treatment for generalized anxiety disorder (GAD).
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether adding ABBV‑932 to your current antidepressant helps your anxiety and is safe.
- Who it's for
- You may be able to join if you are an adult with generalized anxiety disorder and your current antidepressant isn’t working well enough.
- What's involved
- You will take a capsule of ABBV‑932 or a pretend pill every day for 6 weeks while you keep taking your usual antidepressant. You will visit a clinic several times for check‑ups, blood tests, and to fill out questionnaires about how you feel.
- Time commitment
- The study lasts 10 weeks total: 6 weeks of taking the pill and 4 weeks of follow‑up visits.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Meet Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for generalized anxiety disorder (GAD)...
- Currently taking protocol-specified antidepressant therapies (ADT) for GAD with an inadequate response to an adequate dose (per label) and duration...
You likely can't join if
- Have a Montgomery-Åsberg Depression Rating Scale (MADRS) score \>= 20.
- New diagnosis or exacerbation of major depression in the last 6 months.
The study team makes the final eligibility decision.
Where it is enrolling
- Huntsville, Alabama, United States
- Phoenix, Arizona, United States
- Anaheim, California, United States
- Colton, California, United States
- Imperial, California, United States
- Lemon Grove, California, United States
- Long Beach, California, United States
- Los Angeles, California, United States
- Oceanside, California, United States
- Temecula, California, United States
- Walnut Creek, California, United States
- Cromwell, Connecticut, United States
- Jacksonville, Florida, United States
- Largo, Florida, United States
- Maitland, Florida, United States
- Miami, Florida, United States
- Orlando, Florida, United States
- Marietta, Georgia, United States
- Savannah, Georgia, United States
- Chicago, Illinois, United States
+ 26 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Huntsville, Alabama, United States; Phoenix, Arizona, United States; Anaheim, California, United States; Colton, California, United States; Imperial, California, United States; Lemon Grove, California, United States and 40 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.