Clinical trial for Pain, Chronic
Official title Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain
ClinicalTrials.gov ID: NCT06847360
What this study is testing
- What it's testing
- The study will see if using a home device that stimulates the ear nerve is safe and practical for managing IBS pain and symptoms. It will also compare real stimulation to a minimal‑stimulation control.
- Who it's for
- Young adults who have irritable bowel syndrome and experience pain
- What's involved
- Participants will use the device twice a day for 30 minutes each session for six weeks, keep a symptom diary, and visit the lab at the start and end for check‑ups and tests.
- Time commitment
- The study lasts six weeks, with two lab visits and daily use of the device at home.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 29
You may be able to join if
- 18 - 29 years of age;
- Men and women;
- Diagnosis of IBS from a healthcare provider with current report of pain (volunteers asked to bring provider-verification of IBS diagnosis based on...
- Experiencing moderate pain (≥3 out of 10 on numeric rating scale [NRS]) at least 4 days of the week and lasting previous three months;
- Daily access to a computer connected to the internet; and
You likely can't join if
- Other chronic pain condition;
- Celiac disease or inflammatory bowel disease;
- Diabetes mellitus;
- severe psychiatric condition requiring inpatient treatment in previous 6 months;
- Pregnancy or lactation;
- Regular use of opioids or other illicit substances;
See the full eligibility criteria
- 18 - 29 years of age;
- Men and women;
- Diagnosis of IBS from a healthcare provider with current report of pain (volunteers asked to bring provider-verification of IBS diagnosis based on Rome IV criteria to initial study appointment);
- Experiencing moderate pain (≥3 out of 10 on numeric rating scale [NRS]) at least 4 days of the week and lasting previous three months;
- Daily access to a computer connected to the internet; and
- Able to read and speak English.
- Other chronic pain condition;
- Celiac disease or inflammatory bowel disease;
- Diabetes mellitus;
- severe psychiatric condition requiring inpatient treatment in previous 6 months;
- Pregnancy or lactation;
- Regular use of opioids or other illicit substances;
- use of probiotics or antibiotics within 2 weeks from enrollment; and
- any other conditions/contraindications that prohibit the application of taVNS including but not limited to any current or past history of cardiovascular disorders, recent ear trauma, and metal implants above the level...
The study team makes the final eligibility decision.
Where it is enrolling
- New Haven, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 29 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at New Haven, Connecticut, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.