Ischemic Heart Disease study: Gadavist vs Vasodilator
Official title The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study
ClinicalTrials.gov ID: NCT06854458
What this study is testing
What is Gadavist?
an investigational MRI contrast agent being studied for imaging ischemic heart disease is designed to enhance magnetic resonance images by changing the magnetic properties of blood and tissues
Also referred to as Gadobutrol.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to find out whether measuring blood flow during a stress test with cardiac magnetic resonance imaging can diagnose heart disease more accurately than the usual imaging methods.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 35 to 85
You may be able to join if
- male or female at age 35-85 years,
- chest pain or anginal equivalent, or
- abnormal electrocardiogram with a suspicion of coronary artery disease
- Intermediate or high risk of significant coronary disease based on at least 1 of the following conditions: a) patient age \> 45 for male, 50 for...
You likely can't join if
- Acute myocardial infarction within the past 30 days prior to cardiac magnetic resonance imaging
- any severe-grade valvular heart disease,
- left ventricular ejection fraction \<40% from any known non-coronary causes,
- infiltrative cardiomyopathy,
- hypertrophic cardiomyopathy,
- pericardial disease with significant constriction, or
See the full eligibility criteria
- male or female at age 35-85 years,
- chest pain or anginal equivalent, or
- abnormal electrocardiogram with a suspicion of coronary artery disease
- Intermediate or high risk of significant coronary disease based on at least 1 of the following conditions: a) patient age \> 45 for male, 50 for female b) Diabetes, hypertension, or hypercholesterolemia: by either...
- Acute myocardial infarction within the past 30 days prior to cardiac magnetic resonance imaging
- any severe-grade valvular heart disease,
- left ventricular ejection fraction \<40% from any known non-coronary causes,
- infiltrative cardiomyopathy,
- hypertrophic cardiomyopathy,
- pericardial disease with significant constriction, or
- active pregnancy,
- any competing conditions leading to an expected survival of \< 2 years
- contraindication to vasodilator (regadenoson or adenosine)
- metallic device or object that poses an magnetic resonance imaging safety hazard
- metallic device with a high likelihood of non-diagnostic cardiac magnetic resonance images
The study team makes the final eligibility decision.
Where it is enrolling
- San Francisco, California, United States
- Louisville, Kentucky, United States
- Boston, Massachusetts, United States
- Roslyn, New York, United States
- Charlotte, North Carolina, United States
- Cleveland, Ohio, United States
- Columbus, Ohio, United States
- Nashville, Tennessee, United States
- Houston, Texas, United States
- Salt Lake City, Utah, United States
- Charlottesville, Virginia, United States
- Richmond, Virginia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 35 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at San Francisco, California, United States; Louisville, Kentucky, United States; Boston, Massachusetts, United States; Roslyn, New York, United States; Charlotte, North Carolina, United States; Cleveland, Ohio, United States and 6 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.