Clinical trial for Psoriatic Arthritis
Official title Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis
ClinicalTrials.gov ID: NCT06865105
What this study is testing
What is Lutikizumab?
An investigational subcutaneous injectable medicine being studied for psoriatic arthritis.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see how well the drugs risankizumab and lutikizumab, alone or together, work and how safe they are for people with active psoriatic arthritis.
- Who it's for
- Adults who have active psoriatic arthritis and are willing to travel to a study site for visits and tests.
- What's involved
- Participants will receive either lutikizumab, risankizumab, or both, and will have regular clinic visits, blood tests, medical checks, and will fill out questionnaires to track symptoms and side effects.
- Time commitment
- The study lasts several months, with multiple scheduled visits at a hospital or clinic for assessments and blood draws.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Participant is willing and able to comply with procedures required in the Master Protocol and relevant, actively enrolling substudies.
- Participant has a documented clinical diagnosis of PsA with symptom onset at least 6 months prior to the Screening Visit and fulfillment of the...
- Participant has active disease defined as greater than or equal to 3 tender joints (based on 68 joint count) and greater than or equal to 3 swollen...
- Participant has active plaque PsO, with at least one psoriatic plaque of \>= 2 cm diameter or nail changes consistent with PsO at Screening Visit.
- Participant must demonstrate intolerance or inadequate response to 1 to 2 targeted therapies (biologic or targeted synthetic disease-modifying...
You likely can't join if
- Participants who have had major surgery performed within 12 weeks prior to randomization or plan to have a major surgery during conduct of the study...
- Participants with the following active, chronic, or recurring infections: Are infected with human immunodeficiency virus (HIV), active hepatitis B...
- Active skin disease other than psoriasis (PsO) which could interfere with the assessment of PsO.
- History of fibromyalgia, any arthritis with onset prior to age 17 years, or current diagnosis of inflammatory joint disease other than psoriatic...
The study team makes the final eligibility decision.
Where it is enrolling
- Huntington Beach, California, United States
- Avon Park, Florida, United States
- Clearwater, Florida, United States
- Orlando, Florida, United States
- Tamarac, Florida, United States
- Tampa, Florida, United States
- Chicago, Illinois, United States
- Willowbrook, Illinois, United States
- Lebanon, New Hampshire, United States
- Middleburg Heights, Ohio, United States
- Duncansville, Pennsylvania, United States
- Memphis, Tennessee, United States
- Austin, Texas, United States
- Frisco, Texas, United States
- Houston, Texas, United States
- San Antonio, Texas, United States
- Tomball, Texas, United States
- Sherbrooke, Quebec, Canada
- Trois-Rivières, Quebec, Canada
- Saskatoon, Saskatchewan, Canada
+ 14 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Huntington Beach, California, United States; Avon Park, Florida, United States; Clearwater, Florida, United States; Orlando, Florida, United States; Tamarac, Florida, United States; Tampa, Florida, United States and 28 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.