Peripheral Arterial Disease study: Rivaroxaban vs Clopidogrel
Official title VTE Incidence After Rivaroxaban + Aspirin or SAPT After Lower-limb Revascularization
ClinicalTrials.gov ID: NCT06873321
What this study is testing
What is rivaroxaban 2.5 mg bid + aspirin 100 mg?
This is an investigational combination of two blood-thinning pills being studied to help prevent blood clots after leg surgery. It is designed to stop blood cells from sticking together to form clots.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to find out if using rivaroxaban is a safe and effective way to prevent blood clots in the legs or lungs after surgery to improve blood flow in the legs.
- Who it's for
- The study is looking for adults who have peripheral artery disease and are scheduled to have surgery to open up blocked arteries in their legs.
- What's involved
- Participants will take a daily blood thinner pill (rivaroxaban) along with aspirin or other standard heart medications. They will also have regular check-ups and blood tests to monitor for any signs of bleeding or clots.
- Time commitment
- The study involves taking medication for a set period after surgery and attending scheduled follow-up visits to track health outcomes.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults
You may be able to join if
- Be adults of any age and gender.
- Have critical limb ischemia with a proposed revascularization treatment (either via ATP or bypass surgery) at the Vascular Surgery Service of...
- Sign the informed consent form (ICF) (Appendix 2).
You likely can't join if
- Experience a symptomatic VTE event during hospitalization, as they will require full anticoagulation rather than prophylactic anticoagulation.
- Have any contraindications to Rivaroxaban.
- Do not return for the 30-day postoperative follow-up visit.
The study team makes the final eligibility decision.
Where it is enrolling
- Pernambuco, Pernambuco, Brazil
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Pernambuco, Pernambuco, Brazil. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.