Clinical trial for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Official title RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
ClinicalTrials.gov ID: NCT06933173
What this study is testing
- What it's testing
- The study will see if the Dynamic Neural Retraining System helps improve quality of life, fatigue, pain, mood, sleep, and physical activity, and will look at changes in blood chemistry and gut bacteria.
- Who it's for
- Adults diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, with or without Long COVID.
- What's involved
- Participants will take part in the DNRS mind‑body program, complete questionnaires, wear activity trackers, have heart‑rate and sleep monitored, and give blood and stool samples for lab tests.
- Time commitment
- The trial lasts several months, with regular visits for assessments and data collection, and a wait‑list control group that receives the program after the study period.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age 18 years or older;
- Individuals diagnosed with ME/CFS, according to the Institute of Medicine (2015) criteria, for more than six months.
You likely can't join if
- Individuals who: 1) are too ill to participate; 2) lack reliable internet; 3) cannot communicate in English
- Art Therapy
- Autogenic training
- Biofeedback/neurofeedback
- Breathing exercise
- Cognitive restructuring
See the full eligibility criteria
- Age 18 years or older;
- Individuals diagnosed with ME/CFS, according to the Institute of Medicine (2015) criteria, for more than six months.
- Individuals who: 1) are too ill to participate; 2) lack reliable internet; 3) cannot communicate in English; 4) Presently have or ever had inflammatory bowel disease
- Art Therapy
- Autogenic training
- Biofeedback/neurofeedback
- Breathing exercise
- Cognitive restructuring
- Dynamic Neural Retraining System
- Emotional Freedom Techniques (EFT)
- Eye movement desensitization and reprocessing (EMDR)
- Guided imagery
- Hypnotherapy/self-hypnosis
- Meditation (mindfulness, mantra, guided, transcendental)
- Mindfulness-based cognitive therapy (MBCT)
- Mindfulness-based Stress Reduction (MBSR)
- Music therapy
- Neurolinguistic programming
- Psychological flexibility
- Qigong
- Relaxation therapy (relaxation response, progressive muscle relaxation)
- Tai Chi
- Visualization
- untreated hypothyroidism (including Hashimoto's disease)
- hyperthyroidism
- diabetes mellitus
- iron deficiency anemia
- other treatable anemia
- iron overload syndrome
- adrenal insufficiency
- Cushing's syndrome
- anorexia nervosa
- iatrogenic conditions such as side effects or interactions of medication(s) or supplements
- rheumatoid arthritis
- lupus
- polymyositis
- polymyalgia rheumatica
- Sjogren's Syndrome
- Ehlers Danlos Syndromes [Hypermobility type]
- Marfan syndrome
- Stickler syndrome etc.
- Multiple sclerosis
- Celiac disease
- Note: Patients with celiac disease can present without gastrointestinal symptoms
- Immune disorders
- such as HIV/AIDS
- Sleep disorders
- including obstructive sleep apnea
- Prior illnesses may relapse or may not have completely resolved during treatment.
- Examples are certain malignancies
- leukemia
- infectious diseases such as tuberculosis and chronic hepatitis
- Active primary psychiatric disorders
- eating disorders
- alcohol
- substance use disorder
The study team makes the final eligibility decision.
Where it is enrolling
- Calgary, Alberta, Canada
- Edmonton, Alberta, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Calgary, Alberta, Canada; Edmonton, Alberta, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.