Visual Snow Syndrome study: Visual Adaptation vs Magnetic Resonance Imaging
Official title Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
ClinicalTrials.gov ID: NCT06961864
What this study is testing
- What it's testing
- The study wants to find out where in the brain the symptoms of Visual Snow Syndrome come from and how brain activity causes them.
- Who it's for
- It is looking for adults who have Visual Snow Syndrome, adults who have migraine, and adults who are healthy.
- What's involved
- Participants will fill out questionnaires about their vision and mental health, look at pictures while making judgments, and have their brain scanned with an MRI.
- Time commitment
- The study lasts about a few hours for each visit, with one main visit that includes questionnaires, picture tasks, and an MRI scan.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Between the ages of 18 and 60 years old
- Normal (20/25 or better in each eye) or corrected-to-normal vision (MR-compatible glasses will be provided as needed)
- Ability to comply with study instructions
- Individuals who have a current diagnosis of VSS from a neuro-ophthalmologist or meet diagnostic criteria of VSS (experience of dynamic dots across...
- Between the ages of 18 and 60 years old
You likely can't join if
- Not being fluent in English or another language for which interpretation/translation services are available
- A diagnosed or self-reported intellectual disability
- Current substance dependence (besides nicotine), or drug dependence with tolerance or withdrawal within past 12 months
- Hallucinogenic substance use within the past 12 months or hallucinogenic substance use within 12 months prior to onset of VSS symptoms
- Severe central nervous system disease
- Head injury with skull fracture or loss of consciousness for more than thirty minutes
See the full eligibility criteria
- Between the ages of 18 and 60 years old
- Normal (20/25 or better in each eye) or corrected-to-normal vision (MR-compatible glasses will be provided as needed)
- Ability to comply with study instructions
- Individuals who have a current diagnosis of VSS from a neuro-ophthalmologist or meet diagnostic criteria of VSS (experience of dynamic dots across the visual field persisting longer than 3 months and at least 2 of the...
- Between the ages of 18 and 60 years old
- Normal (20/25 or better in each eye) or corrected-to-normal vision (MR-compatible glasses will be provided as needed)
- Ability to comply with study instructions
- Individuals living in Minnesota within 2 hours of the study site
- Not being fluent in English or another language for which interpretation/translation services are available
- A diagnosed or self-reported intellectual disability
- Current substance dependence (besides nicotine), or drug dependence with tolerance or withdrawal within past 12 months
- Hallucinogenic substance use within the past 12 months or hallucinogenic substance use within 12 months prior to onset of VSS symptoms
- Severe central nervous system disease
- Head injury with skull fracture or loss of consciousness for more than thirty minutes
- Presence of a physical problem that would render study measures difficult or impossible to administer or interpret (e.g., visual field loss)
- Age less than 18 years or greater than 60 years
- Metal in the body that cannot be approved by the CMRR safety committee
- Pregnancy
- Conditions that affect neuro-hemodynamic coupling
- Claustrophobia
- Inability to lie still for at least an hour
- Weight in excess of 440 lbs
- CT scan exclusion only: Research-related radiation exposure within the last 12 months
- Any vision anomaly aside from VS or refractive error (e.g., strabismus/ crossed eyes, lazy eyes, color blindness)
- Not being fluent in English or another language for which interpretation/translation services are available
- A diagnosed or self-reported intellectual disability
- Current substance dependence (besides nicotine), or drug dependence with tolerance or withdrawal within past 12 months
- Hallucinogenic substance use within the past 12 months
- Severe central nervous system disease
- Head injury with skull fracture or loss of consciousness for more than thirty minutes
- Presence of a physical problem that would render study measures difficult or impossible to administer or interpret (e.g., visual field loss)
- Age less than 18 years or greater than 60 years
- Metal in the body that cannot be approved by the CMRR safety committee
- Pregnancy
- Conditions that affect neuro-hemodynamic coupling
- Claustrophobia
- Inability to lie still for at least an hour
- Weight in excess of 440 lbs
- CT scan exclusion only: Research-related radiation exposure within the last 12 months
- Any vision anomaly or refractive error (e.g. strabismus/ crossed eyes, lazy eyes, color blind)
- A personal history of VSS symptoms or a diagnosis with VSS
- Current psychotic episode
The study team makes the final eligibility decision.
Where it is enrolling
- Minneapolis, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Minneapolis, Minnesota, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.