Clinical trial for Posttraumatic Stress Disorder (PTSD)
Official title Project COMET: Massed Prolonged Exposure for PTSD and SUD
ClinicalTrials.gov ID: NCT06968832
What this study is testing
- What it's testing
- The study wants to find out if Massed Prolonged Exposure Therapy works better than usual trauma care at lowering PTSD symptoms and substance‑use days, and how it affects depression, suicidal thoughts, and quality of life.
- Who it's for
- Adults who are already in an intensive outpatient program for substance use disorder and also have PTSD.
- What's involved
- Participants will attend several therapy sessions each week of the new exposure therapy or receive standard trauma care, and they will complete questionnaires and interviews at several time points.
- Time commitment
- The study lasts about 6 months, with visits for therapy and assessments at baseline, during treatment, at the end of treatment, and at 1‑, 3‑, and 6‑month follow‑ups.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age 18+
- Enrolled in SUD treatment at Gateway Community Services
- Meet DSM-5 criteria for a SUD (Tobacco Use Disorder alone not sufficient for inclusion)
- Meet DSM-5 criteria for PTSD
- Able to give informed consent
You likely can't join if
- severe cognitive impairment
- current suicidal or homicidal intent requiring immediate treatment
- current unstable psychotic or manic symptoms not attributable to SUD
The study team makes the final eligibility decision.
Where it is enrolling
- Jacksonville, Florida, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Jacksonville, Florida, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.