Rheumatoid Arthritis study: Lutikizumab vs Ravagalimab
Official title A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
ClinicalTrials.gov ID: NCT06972446
What this study is testing
What is Lutikizumab?
An investigational subcutaneous injection being studied for the treatment of rheumatoid arthritis.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see how safe and effective different new drugs are for treating rheumatoid arthritis that still hurts and limits joint function.
- Who it's for
- It is looking for adults who have rheumatoid arthritis that has not fully responded to 1 or 2 previous biologic or targeted synthetic disease‑modifying drugs.
- What's involved
- Participants will receive one of several study drugs or a placebo, have regular clinic visits, blood tests, and questionnaires to monitor safety and effectiveness.
- Time commitment
- The study lasts about a year, with multiple clinic visits throughout to check progress and side effects.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- At any time prior to the Screening Visit, participant must have been treated for \> or = 3 months with at least 1 b/tsDMARD therapy but continued to...
- Participant must be on a stable dose of methotrexate (MTX)
You likely can't join if
- Participant is taking nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen/paracetamol, low-potency opioids (tramadol, codeine, hydrocodone...
- History of any arthritis with onset prior to age 17 years or current diagnosis of inflammatory joint disease other than rheumatoid arthritis.
The study team makes the final eligibility decision.
Where it is enrolling
- Peoria, Arizona, United States
- Jonesboro, Arkansas, United States
- Beverly Hills, California, United States
- Chula Vista, California, United States
- Huntington Beach, California, United States
- Thousand Oaks, California, United States
- Torrance, California, United States
- Upland, California, United States
- Fort Collins, Colorado, United States
- Avon Park, Florida, United States
- Clearwater, Florida, United States
- Greenacres City, Florida, United States
- Hialeah, Florida, United States
- Hollywood, Florida, United States
- Jacksonville, Florida, United States
- Margate, Florida, United States
- Orlando, Florida, United States
- Palm Beach Gardens, Florida, United States
- Tampa, Florida, United States
- Chicago, Illinois, United States
+ 62 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Peoria, Arizona, United States; Jonesboro, Arkansas, United States; Beverly Hills, California, United States; Chula Vista, California, United States; Huntington Beach, California, United States; Thousand Oaks, California, United States and 76 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.