Dysphagia study: Esophageal string test
Official title The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States
ClinicalTrials.gov ID: NCT07027826
What this study is testing
- What it's testing
- The study wants to see if the esophageal string test can identify eosinophilic esophagitis, a condition that inflames the esophagus, in people who have trouble swallowing.
- Who it's for
- Adults 18‑65 years old who have swallowing difficulties and were born in Africa or have parents born in Africa.
- What's involved
- Participants will give blood, stool, urine, and a skin swab, fill out health and diet surveys, bring a water sample, and undergo the string test where a nylon string is swallowed and later retrieved for analysis. They will also have a standard endoscopy at a separate visit and finish with a final survey or interview.
- Time commitment
- The study lasts about a week, with multiple visits for sample collection, the string test, an endoscopy, and a final follow‑up interview or survey.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Able to provide informed consent.
- Aged 18 to 65 years.
- Born in the African continent or their parents were born in Africa,
- Exhibiting symptoms of dysphagia and/or prior history of food impaction.
- Undergoing clinically indicated endoscopy at the NIH Clinical Center (U.S.), Centre Hospitalier Universitaire Gabriel Tour(SqrRoot)(Copyright)...
You likely can't join if
- Recent steroid use (systemic or swallowed/topical corticosteroid) within 4 weeks prior to endoscopy.
- Recent use of dupilumab (Dupixent) within the last 6 months.
- Recent use of other biologic medications (within either 6 months or 5 half-lives, whichever is longer). Examples of biologic medications include: 3a.
The study team makes the final eligibility decision.
Where it is enrolling
- Bethesda, Maryland, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Bethesda, Maryland, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.