Acute Coronary Syndrome study: Polypill
Official title A Polypill for Acute Coronary Syndrome
ClinicalTrials.gov ID: NCT07032389
What this study is testing
What is Polypill?
Polypill is an investigational medicine, taken by mouth once daily, being studied as a potential treatment for acute coronary syndrome.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The current study aims to investigate whether combining the standard medications prescribed after acute coronary syndrome (ACS)-aspirin, P2Y12 inhibitors, and statins-into a single polypill can improve outcomes following an ACS event. Although these therapies are effective, gaps in adherence and uptake significantly contribute to risk or adverse events in the post-ACS period.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18
- Hospitalization for acute coronary syndrome with percutaneous coronary intervention
- Discharged on aspirin, prasugrel or clopidogrel, and a high-intensity statin
You likely can't join if
- Current need for systemic anticoagulation
- Contraindication to receive any components of the polypill
- History of allergic reaction or intolerance to aspirin, prasugrel or clopidogrel, or rosuvastatin
- Comorbidities that might be expected to limit lifespan within the 12-month study period
- Increased risk of bleeding or planned urgent surgery that would necessitate use of DAPT for \< 12 months
- Inability to provide written informed consent
See the full eligibility criteria
- Age ≥ 18
- Hospitalization for acute coronary syndrome with percutaneous coronary intervention
- Discharged on aspirin, prasugrel or clopidogrel, and a high-intensity statin
- Current need for systemic anticoagulation
- Contraindication to receive any components of the polypill
- History of allergic reaction or intolerance to aspirin, prasugrel or clopidogrel, or rosuvastatin
- Comorbidities that might be expected to limit lifespan within the 12-month study period
- Increased risk of bleeding or planned urgent surgery that would necessitate use of DAPT for \< 12 months
- Inability to provide written informed consent
- Pregnancy
The study team makes the final eligibility decision.
Where it is enrolling
- Dallas, Texas, United States
Compensation & support
A stipend or payment for your time may be offered.
No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team, so confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Dallas, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.