Alcohol Use Disorder study: Semaglutide
Official title Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide
ClinicalTrials.gov ID: NCT07040592
What this study is testing
What is semaglutide?
This is an investigational medicine being studied to see if it can help reduce alcohol use in people with HIV and alcohol use disorder. It is designed to slow down how quickly your stomach empties and signal to your brain that you are full.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study checks if using semaglutide along with medical care and support is a practical and helpful way to lower alcohol use.
- Who it's for
- People who have both HIV and a problem with alcohol use.
- What's involved
- Participants will take semaglutide, receive medical management, and work with a clinical pharmacist on a plan to change behavior.
- Time commitment
- The source text does not specify the duration or number of visits.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 99
You may be able to join if
- diagnosed with HIV
- Receive care at the Atlanta VA Healthcare System
- Age 18 or over
- Meet criteria for mild, moderate, or severe alcohol use disorder by the DSM-5 Alcohol Symptom Checklist and the Alcohol Use Disorders Identification...
- Have evidence of significant alcohol use: PEth \> 20ng/ml
You likely can't join if
- Active engagement in formal alcohol treatment including medications for alcohol use disorder at the time of enrollment
- Self-report or laboratory test confirming pregnancy, nursing, or trying to conceive
- Life-threatening or unstable medical, surgical, or psychiatric condition that prohibits participation (including current or past intent to harm...
- Untreated moderate to severe opioid use disorder
- Residence out of state
- Inability to read or understand English
See the full eligibility criteria
- diagnosed with HIV
- Receive care at the Atlanta VA Healthcare System
- Age 18 or over
- Meet criteria for mild, moderate, or severe alcohol use disorder by the DSM-5 Alcohol Symptom Checklist and the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) screen
- Have evidence of significant alcohol use: PEth \> 20ng/ml
- Prescribed \>=5 medications
- Have cell phone or reliable contact number
- Can provide written informed consent
- Active engagement in formal alcohol treatment including medications for alcohol use disorder at the time of enrollment
- Self-report or laboratory test confirming pregnancy, nursing, or trying to conceive
- Life-threatening or unstable medical, surgical, or psychiatric condition that prohibits participation (including current or past intent to harm oneself or others within the prior 12 months and not receiving treatment)
- Untreated moderate to severe opioid use disorder
- Residence out of state
- Inability to read or understand English
- History of serious hypersensitivity or adverse reaction to study medication
- Taking potentially interactive medication(s) for diabetes
- BMI\<23
- Diagnosis of type 1 Diabetes
- Personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, Severe gastrointestinal dysmotility, including gastroparesis, History of pancreatitis (does not pertain to...
- Known Proliferative Diabetic Retinopathy, severe Non-Proliferative Diabetic Retinopathy, clinically significant Macular Edema, or Cystoid Macular Edema
- Already prescribed the pilot medication at the time of study recruitment.
The study team makes the final eligibility decision.
Where it is enrolling
- Decatur, Georgia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Decatur, Georgia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.