Epilepsy study: Sodium valproate
Official title Pharmacogenetics-Based Study on Individualized Use of Sodium Valproate
ClinicalTrials.gov ID: NCT07046676
What this study is testing
What is sodium valproate?
sodium valproate is an investigational medicine, taken by mouth twice daily, being studied as a potential treatment for epilepsy.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Sodium valproate (VPA) is a first-line prescription drug widely used in the treatment of epilepsy. However, in clinical applications, it has been found that there is a large individual variation in the blood concentration of VPA.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults
You may be able to join if
- Patients diagnosed with epilepsy (primary epilepsy, secondary epilepsy) and with complete clinical data
- Regular use of valproic acid sodium for at least 5 days (with blood drug concentration reaching a steady state) and strong medication compliance
- Patients using combined anti-epileptic drugs or using valproic acid sodium alone
- Patients without significant liver or kidney dysfunction, and not in the pregnancy period
You likely can't join if
- Patients with incomplete data, poor compliance, and those whose blood drug concentration was not measured at the correct concentration
- Patients with major respiratory, gastrointestinal, liver, kidney or other serious diseases
- Patients using valproic acid solely for epilepsy prevention
- Patients who have used valproic acid for more than 5 days but have frequently changed the dosage form during the process
- Patients over 65 years old and in the 1CU
The study team makes the final eligibility decision.
Where it is enrolling
- Hengyang, Hunan, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Hengyang, Hunan, China. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.