Clinical trial for Oral Epithelial Dysplasia (OED)
Official title Evaluating Treatment Strategies for p53 Mutant Oral Cancer and Oral Cancer Precursors
ClinicalTrials.gov ID: NCT07090070
What this study is testing
- What it's testing
- The study wants to find which treatment works best at each stage of p53‑mutant oral lesions, from low‑grade dysplasia to early cancer.
- Who it's for
- It looks for adults who have p53‑mutant oral epithelial dysplasia or early oral squamous cell carcinoma.
- What's involved
- Participants will be randomly given one of two options in each group: for example, watchful waiting or surgery, or surgery with different margin goals, or surgery with or without neck dissection. They will have regular visits and tests to monitor their condition.
- Time commitment
- The study lasts up to 4 years, with scheduled visits and follow‑up exams to track disease progression and outcomes.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adults age 18 or over
- No history of head and neck radiation
- T1 SCC with depth of Invasion (DOI) \<4mm
- Clinically and radiologically node-negative (confirmed by contrast-enhanced CT)
You likely can't join if
- Immunocompromised status
- Lesions greater than 3 cm
- Positive nodes on contrast-enhanced CT
- DOI \>= 4mm
The study team makes the final eligibility decision.
Where it is enrolling
- Vancouver, British Columbia, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Vancouver, British Columbia, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.