Recruiting at 18 sites Phase 2 Hypertension

Hypertension study: Iloperidone

Official title Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

ClinicalTrials.gov ID: NCT07090161

What this study is testing

What is iloperidone?

This is an investigational medicine being studied to see if it can help treat uncontrolled high blood pressure.

Also referred to as Fanapt.

Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
This study is testing whether iloperidone works to lower blood pressure. It also checks how safe the drug is.
Who it's for
You may be able to join if you have high blood pressure that is hard to control.
What's involved
You would take a pill every day. You would also get regular check-ups to monitor your health.
Time commitment
The study lasts for a set time with regular visits to the clinic.
  • Phase 2: a mid-size study of how well it works
  • You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 65

You may be able to join if

  • SiSBP \>/= 130 mmHg despite \>8 weeks treatment w/ 1 or more antihypertensive therapies

You likely can't join if

  • Confirmed Grade 3/severe hypertension (SiSBP \>/= 180 mmHg, SiDBP \>/= 120 mmHg), unstable cardiac disease, renal insufficiency

The study team makes the final eligibility decision.

Where it is enrolling

  • Tempe, Arizona, United States
  • Chula Vista, California, United States
  • Dublin, California, United States
  • Walnut Creek, California, United States
  • Fort Myers, Florida, United States
  • Columbus, Georgia, United States
  • Oak Brook, Illinois, United States
  • Tinley Park, Illinois, United States
  • El Dorado, Kansas, United States
  • Wichita, Kansas, United States
  • Lexington, Kentucky, United States
  • Hazelwood, Missouri, United States
  • Kinston, North Carolina, United States
  • Cincinnati, Ohio, United States
  • Norman, Oklahoma, United States
  • Charleston, South Carolina, United States
  • Burke, Virginia, United States
  • Norfolk, Virginia, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.

Where is this trial taking place?

This study is enrolling now at Tempe, Arizona, United States; Chula Vista, California, United States; Dublin, California, United States; Walnut Creek, California, United States; Fort Myers, Florida, United States; Columbus, Georgia, United States and 12 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.