Clinical trial for Oral Cancer
Official title Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain
ClinicalTrials.gov ID: NCT07095608
What this study is testing
- What it's testing
- The study aims to find out how pain sensitivity differs between people with oral cancer and people without it.
- Who it's for
- Adults with oral squamous cell carcinoma and healthy adults without cancer.
- What's involved
- Participants will have pain stimulation applied to the cancer site (or the tongue for volunteers) using pressure and stretch tests, and their sensitivity will be measured.
- Time commitment
- A single testing session lasting about an hour.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Provide signed and dated informed consent form
- Willing to comply with all study procedures and be available for the duration of the study
- Male or female, at least 18 years of age
- Provide signed and dated informed consent form
- Willing to comply with all study procedures and be available for the duration of the study
You likely can't join if
- Clinically and/or histologically proven oral pre-cancer, oral cancer
- Pregnancy or lactation (Female people of child-bearing potential will have a rapid urine pregnancy test)
- History of prior surgical, chemotherapeutic, or radiation treatment for head and neck cancer
- Pregnancy or lactation
- Anything that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study.
See the full eligibility criteria
- Provide signed and dated informed consent form
- Willing to comply with all study procedures and be available for the duration of the study
- Male or female, at least 18 years of age
- Provide signed and dated informed consent form
- Willing to comply with all study procedures and be available for the duration of the study
- Male or female, at least 18 years of age
- Biopsy-proven squamous cell carcinoma (SCC) of the oral cavity that requires surgical resection
- Lesion is at least 1 cm in greatest surface dimension
- Clinically and/or histologically proven oral pre-cancer, oral cancer
- Pregnancy or lactation (Female people of child-bearing potential will have a rapid urine pregnancy test)
- History of prior surgical, chemotherapeutic, or radiation treatment for head and neck cancer
- Pregnancy or lactation
- Anything that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study.
The study team makes the final eligibility decision.
Where it is enrolling
- New York, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at New York, New York, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.