Localized Anal Carcinoma study: Fluoroscopy vs Ganglion Impar Neurolysis
Official title Ganglion Impar Neurolysis for the Improvement of Radiation-Induced Pain During Localized Anal or Perianal Skin Cancer Treatment
ClinicalTrials.gov ID: NCT07112690
What this study is testing
- What it's testing
- The study wants to see if ganglion impar neurolysis can lessen pain caused by combined chemotherapy and radiation therapy.
- Who it's for
- It is looking for adults with localized anal or perianal skin cancer that has not spread to other parts of the body.
- What's involved
- Participants will receive a nerve block procedure near the tailbone that injects medicine to numb pain‑sensing nerves, while continuing their usual cancer treatment.
- Time commitment
- The study lasts as long as the radiation treatment, with visits for the nerve block and routine follow‑up appointments.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients must have diagnosis of localized anal cancer or perianal skin cancer and have either initiated or about to initiated definitive chemotherapy...
- Patients who are consistently reporting pain scores of 5 or higher or reporting high pain interference or distress will be approached to participate...
- Age \> 18 years. Given the rarity of anal cancer in children, children are excluded from this study
- Eastern Cooperative Oncology Group (ECOG) performance status =\ 60%)
- Life expectancy of greater than \> 12 months
You likely can't join if
- Absolute neutrophil count less than 1500
- Platelet count less 80,000
See the full eligibility criteria
- Patients must have diagnosis of localized anal cancer or perianal skin cancer and have either initiated or about to initiated definitive chemotherapy and radiation therapy for their cancer
- Patients who are consistently reporting pain scores of 5 or higher or reporting high pain interference or distress will be approached to participate in the study
- Age \> 18 years. Given the rarity of anal cancer in children, children are excluded from this study
- Eastern Cooperative Oncology Group (ECOG) performance status =\ 60%)
- Life expectancy of greater than \> 12 months
- Ability to understand and the willingness to sign a written informed consent document
- Inclusion of women and minorities: Both men and women and members of all races and ethnic groups are eligible for this trial
- Willingness and ability of the subject to complete the questionnaire
- Previous cancer diagnosis (such as colon or previously resected anal cancer) is permitted
- A diagnosis of HIV or immunocompromised status is permitted
- Absolute neutrophil count less than 1500
- Platelet count less 80,000
The study team makes the final eligibility decision.
Where it is enrolling
- Atlanta, Georgia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Atlanta, Georgia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.