Clinical trial for First Episode Psychosis
Official title Recovery With Exogenous Ketones and Antipsychotics
ClinicalTrials.gov ID: NCT07122531
What this study is testing
- What it's testing
- This study aims to find out if taking a specific type of oil improves blood sugar levels and brain energy in people with early-stage psychosis.
- Who it's for
- The study is looking for young adults who are experiencing their first episode of psychosis.
- What's involved
- Participants will take 15 grams of medium-chain triglyceride (MCT) oil twice a day for 12 weeks, in addition to their usual diet and medication.
- Time commitment
- The study lasts 12 weeks and involves regular check-ins to monitor health and blood sugar levels.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35
You may be able to join if
- Referred or self-referred to the PEP Clinic of the Estrie region, either as an outpatient or inpatient.
- Currently receiving a second- or third-generation antipsychotic at a stable dose for at least 4 weeks.
- Able to read and communicate in French or English.
- Capable of understanding and signing the informed consent form.
You likely can't join if
- Pregnancy, childbirth within the past 6 months, or breastfeeding.
- any use of MCT oil, ketone salts, or a ketogenic diet within the past year.
- Previous diagnosis of type I or type II diabetes.
- Uncontrolled acute suicidal ideation at the time of inclusion in the PEP clinic.
- Other conditions that may interfere with participation, as determined by the qualified physician.
- Pancreatitis (inflammation of the pancreas) or liver failure.
See the full eligibility criteria
- Referred or self-referred to the PEP Clinic of the Estrie region, either as an outpatient or inpatient.
- Currently receiving a second- or third-generation antipsychotic at a stable dose for at least 4 weeks.
- Able to read and communicate in French or English.
- Capable of understanding and signing the informed consent form.
- Pregnancy, childbirth within the past 6 months, or breastfeeding.
- any use of MCT oil, ketone salts, or a ketogenic diet within the past year.
- Previous diagnosis of type I or type II diabetes.
- Uncontrolled acute suicidal ideation at the time of inclusion in the PEP clinic.
- Other conditions that may interfere with participation, as determined by the qualified physician.
- Pancreatitis (inflammation of the pancreas) or liver failure.
- Metabolic condition affecting fat metabolism or inherited carnitine deficiency and its related enzymes.
- Porphyria.
- Pyruvate kinase deficiency.
- Neurodevelopmental disorder of unknown etiology or rare genetic disease.
The study team makes the final eligibility decision.
Where it is enrolling
- Sherbrooke, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 35 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Sherbrooke, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.