Clinical trial for Asthma
Official title The Study About the Identification of Treatable Traits of Severe Asthma and the Construction of Personalized Treatment System
ClinicalTrials.gov ID: NCT07136025
What this study is testing
- What it's testing
- This study is testing whether a personalized treatment plan based on specific asthma traits works better than usual care for people with severe asthma.
- Who it's for
- You may be able to join if you have severe asthma and live in a tertiary hospital in the country.
- What's involved
- You will have tests like lung function, a breath test, blood work, a chest scan, and a questionnaire. Then you will meet with doctors and decide on a personalized treatment plan. You will also be part of a group that gets the usual care for comparison.
- Time commitment
- The study lasts 6 months and includes several visits for tests and follow‑up appointments.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Age ≥18 years, and \<80 years with a definite diagnosis of asthma for at least 6 months
- Patients met the 2024 GINA criteria for severe asthma, which was defined as "uncontrolled" asthma (frequent asthma symptoms, or frequent acute...
- They were willing to accept multi-disciplinary and multi-dimensional evaluation and signed informed consent
- Informed consent was obtained and patients were able to participate in the study and 6-month follow-up according to the protocol
You likely can't join if
- The presence of numerous other lung tissue destructive diseases, such as severe bronchiectasis or pulmonary tuberculosis.
- Chest surgery or abdominal surgery in the past 3 months
- Eye surgery had been performed within the past 3 months
- Myocardial infarction within the previous 3 months
- Anti-tuberculosis treatment is ongoing
- Women who are pregnant and lactating
See the full eligibility criteria
- Age ≥18 years, and \<80 years with a definite diagnosis of asthma for at least 6 months
- Patients met the 2024 GINA criteria for severe asthma, which was defined as "uncontrolled" asthma (frequent asthma symptoms, or frequent acute exacerbations) despite high-dose inhaled corticosteroids (ICS) plus...
- They were willing to accept multi-disciplinary and multi-dimensional evaluation and signed informed consent
- Informed consent was obtained and patients were able to participate in the study and 6-month follow-up according to the protocol
- The presence of numerous other lung tissue destructive diseases, such as severe bronchiectasis or pulmonary tuberculosis.
- Chest surgery or abdominal surgery in the past 3 months
- Eye surgery had been performed within the past 3 months
- Myocardial infarction within the previous 3 months
- Anti-tuberculosis treatment is ongoing
- Women who are pregnant and lactating
- Macrolide use within 4 weeks before the screening period
- Treatment with anti-ige, anti-IL-5, or anti-IL-5R within 4 weeks before the screening period
- Inhaled ICS+LABA+ long-acting anticholinergic agent (LAMA) for 4 weeks prior to the screening period 4. Allergy to macrolides
- QTc interval prolongation \>480ms
- Taking medications that interact with azithromycin, causing QTc prolongation or existing ECG abnormalities, may lead to arrhythmia
The study team makes the final eligibility decision.
Where it is enrolling
- Beijing, Beijing Municipality, China
- Guangzhou, Guangdong, China
- Zhengzhou, Henan, China
- Changsha, Hunan, China
- Shenyang, Liaoning, China
- Shanghai, Shanghai Municipality, China
- Taiyuan, Shanxi, China
- Hangzhou, Zhejiang, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Beijing, Beijing Municipality, China; Guangzhou, Guangdong, China; Zhengzhou, Henan, China; Changsha, Hunan, China; Shenyang, Liaoning, China; Shanghai, Shanghai Municipality, China and 2 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.